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Table 3 Outcomes According to Subgroups

From: Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study

 

All Patients

Brain

Spine

p value

All patients

PPC

No PPC

p value

All patients

ARISCAT < 26

ARISCAT ≥ 26

p value

n (%)

784 (100.0)

376 (48.0)

408 (52.0)

 

777 (100.0)

81 (10.4)

696 (89.6)

 

748 (100.0)

548 (73.3)

200 (26.7)

 

PPCs, n (%)

PPCs

81 (10.4)

46 (12.4)

35 (8.6)

0.085

777 (100.0)

81 (10.4)

696 (89.6)

0.000

80 (10.8)

43 (7.9)

37 (18.6)

0.000

Need of oxygen

69 (8.9)

38 (10.2)

31 (7.6)

0.202

81 (10.4)

81 (100.0)

0 (0.0)

0.000

68 (9.2)

39 (7.2)

29 (14.6)

0.002

Respiratory failure

14 (1.8)

8 (2.2)

6 (1.5)

0.478

69 (8.9)

69 (85.2)

0 (0.0)

0.000

14 (1.9)

6 (1.1)

8 (4.0)

0.010

NIV

9 (1.2)

4 (1.2)

5 (1.2)

0.963

14 (1.8)

14 (17.3)

0 (0.0)

0.000

9 (1.3)

7 (1.3)

2 (1.1)

0.801

ARDS

1 (0.1)

1 (0.3)

0 (0.0)

0.295

9 (1.2)

5 (6.3)

4 (0.6)

0.003

1 (0.1)

0 (0.0)

1 (0.5)

0.098

Pneumothorax

1 (0.1)

1 (0.3)

0 (0.0)

0.295

1 (0.1)

1 (1.2)

0 (0.0)

0.003

1 (0.1)

0 (0.0)

1 (0.5)

0.098

Secondary outcomes, n (%)

Severe PPCs

19 (2.4)

13 (3.5)

6 (1.5)

0.068

19 (2.4)

19 (23.5)

0 (0.0)

0.000

19 (2.6)

6 (1.1)

13 (6.5)

0.000

Intra-operative complications

344 (43.9)

154 (41.1)

190 (46.6)

0.121

342 (44.1)

46 (56.8)

296 (42.6)

0.015

336 (44.9)

237 (43.2)

99 (49.5)

0.128

Desaturation

38 (4.9)

23 (6.1)

15 (3.7)

0.110

37 (4.8)

11 (13.6)

26 (3.7)

0.000

36 (4.8)

21 (3.8)

15 (7.5)

0.038

Unplanned RMs

25 (3.2)

15 (4.0)

10 (2.5)

0.220

24 (3.1)

5 (6.2)

19 (2.7)

0.091

22 (2.9)

12 (2.2)

10 (5.0)

0.043

Pressure reduction

25 (3.2)

11 (2.9)

14 (3.4)

0.692

25 (3.2)

3 (3.7)

22 (3.2)

0.795

22 (2.9)

17 (3.1)

5 (2.5)

0.666

Flow limitation

5 (0.6)

3 (0.8)

2 (0.5)

0.590

4 (0.5)

1 (1.3)

3 (0.4)

0.322

4 (0.5)

2 (0.4)

2 (1.0)

0.289

Hypotension

275 (35.1)

117 (31.2)

158 (38.7)

0.028

274 (35.3)

34 (42.0)

240 (34.5)

0.185

270 (36.1)

197 (35.9)

73 (36.5)

0.890

Vasopressors

245 (31.3)

104 (27.7)

141 (34.6)

0.040

244 (31.4)

37 (45.7)

207 (29.8)

0.004

242 (32.4)

168 (30.7)

74 (37.0)

0.101

New arrhythmias

9 (1.1)

6 (1.6)

3 (0.7)

0.257

9 (1.2)

0 (0.0)

9 (1.3)

0.303

9 (1.2)

5 (0.9)

4 (2.0)

0.227

Hospital LOS, days, median (IQR)

2 (1; 5)

2 (1; 5)

2 (1; 5)

0.993

2 (1; 5)

3 (1; 5)

2 (1; 5)

0.447

2 (1; 5)

2 (1; 5)

3 (1; 5)

0.033

Hospital mortality

5 (0.7)

4 (1.2)

1 (0.3)

0.145

5 (0.7)

1 (1.3)

4 (0.6)

0.500

5 (0.7)

1 (0.2)

4 (2.2)

0.006

  1. n Number, IQR Interquartile range, PPCs Postoperative pulmonary complications, NIV Non-invasive ventilation, ARDS Acute respiratory distress syndrome, LOS Length of hospital stay, RMs Recruitment maneuvers, ARISCAT Assess respiratory risk in surgical patients in Catalonia