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Table 1 Statistically significant ≥10% decreases of 9 cytokines in the dexmedetomidine group

From: The influence of dexmedetomidine and propofol on circulating cytokine levels in healthy subjects

Cytokine

Baseline pg/ml [median (IQR)]

Anesthesia pg/ml [(median (IQR)]

Unadjusted p-value

Adjusted p-value

MCP-1

40 (16)

30 (12)

< 0.001

< 0.001

CTACK

776 (171)

608 (227)

< 0.001

0.002

MIF

180 (160)

123 (160)

< 0.001

< 0.001

Eotaxin

77 (52)

64 (48)

< 0.001

< 0.001

SCF

64 (15)

56 (16)

< 0.001

< 0.001

IL-18

44 (22)

36 (15)

0.012

0.038

IL-2rα

42 (17)

34 (12)

0.006

0.018

VEGF

54 (62)

47 (42)

0.016

0.04

SCGF

16,305 (4218)

13,006 (4003)

< 0.001

< 0.001

  1. Data were analyzed using nonparametric testing due to the skewed distributions and the outlying observations. The median as well as the inter quartile range (IQR) values are reported for each cytokine. The unadjusted p-values were calculated using Wilcoxon signed rank test and the adjusted p-values were calculated using Benjamini-Hochberg method (42 hypothesis tests) controlling for a false discovery rate at 0.05