Total (n = 35) | No and minor complications (n = 25) | Major complications (n = 10) | P | |
---|---|---|---|---|
Age, years | 67 (55–76) | 61 (53–73) | 75 (58–82) | 0.125 |
Female | 25 (71) | 18 (72) | 7 (70) | 0.100 |
BMI Clinical presentation | 26 (24–31) | 27 (27–32) | 24 (21–29) | 0.213 |
ASA | 4 (3–4) | 4.0 (3–4) | 4.0 (3.75–5) | 0.313 |
ICU before rupture | 19 (54.3) | 14 (56) | 5 (50) | 0.100 |
CPR before rupture | 7 (20) | 5 (20) | 2 (20) | 0.100 |
SAPS II | 52 (36–58) | 49 (33–58) | 56 (49–67) | 0.339 |
SOFA | 7 (4–9) | 7 (4–9) | 6 (5–9) | 0.567 |
Tear length, cm | 5 (4–6) | 5 (4–6) | 4 (4–6) | 0.737 |
Causative events | 0.438 | |||
Tracheal intubation | 20 (57) | 15 (60) | 5 (50) | |
Emergency intubation | 18 (51) | 13 (52) | 5 (50) | |
Tracheotomy | 9 (26) | 7 (28) | 2 (20) | |
Surgery | 6 (17) | 3 (12) | 3 (30) | |
Interfacility EMS referral | 17 (49) | 11 (44) | 6 (60) | 0.392 |
Process times | ||||
Rupture to surgery, days | 0.3 (0.2–1.0) | 0.3 (0.2–0.8) | 0.7 (0.2–3.4) | 0.272 |
Anesthesia, minutes | 172 (128–261) | 160 (125–209) | 243 (149–304) | 0.093 |
Surgery, minutes | 100 (68–162) | 97 (64–121) | 141 (78–222) | 0.265 |
OLV, minutes | 52 (40–99) | 55 (40–91) | 63 (46–109) | 0.401 |
Anesthesia management | ||||
TIVA | 16 (45.7) | 12 (48) | 4 (40) | 0.723 |
Tube advancement | 27 (77) | 18 (72) | 9 (90) | 0.390 |
DLT | 11 (31) | 4 (4.9) | 0 (0.0) | 0.120 |
Bronchus blocker | 3 (9) | 1 (4) | 2 (20) | 0.190 |
Devices during surgery | 1 (0–2) | 1 (0–2) | 2 (0–2) | 0.388 |
Tracheotomy | ||||
Before surgery | 7 (20) | 4 (16) | 3 (30) | 0.761 |
During surgery | 6 (17) | 5 (20) | 1 (10) | |
After surgery | 7 (20) | 5 (20) | 2 (20) | |
Not performed | 15 (43) | 11 (44) | 4 (40) | |
Respiratory variables | ||||
FiO2 1.0, % | 90 (75–100) | 90 (55–100) | 95 (80–100) | 0.547 |
FiO2 other | 0.62 (0.5–0.8) | 0.6 (0.5–0.75) | 0.65 (0.45–0.8) | 0.961 |
p/f ratio before | 141 (110–219) | 133 (115–212) | 157 (101–315) | 0.860 |
p/f after | 143 (111–153) | 144 (133–154) | 97 (80–236) | 0.042 |
SaO2 lowest, % | 76 (54–85) | 84 (65–88) | 54 (24–72) | 0.002 |
etCO2 highest, mmHg | 46 (41–59) | 45 (40–59) | 51 (42–60) | 0.410 |
PIP highest, mmHg | 25 (25–28) | 25 (25–29) | 25 (25–28) | 0.621 |
PEEP highest, mmHg | 10 (8–12) | 10 (8–11) | 10 (8–12) | 0.509 |
Circulation | ||||
SBP lowest, mmHg | 74 (52–82) | 80 (70–86) | 40 (0–72) | < 0.001 |
Noradrenaline, μg kg min−1 | 0.18 (0.1–0.31) | 0.10 (0.06–0.22) | 0.22 (0.2–0.84) | a |
Adrenaline | 8 (22.9) | 1 (4) | 7 (70) | a |
Dobutamine | 9 (25.7) | 5 (20) | 4 (40) | 0.398 |
Crystalloid, L | 2 (1–2.5) | 1.5 (1–2) | 2.5 (1–4) | 0.009 |
Transfusion | 14 (40) | 8 (32) | 6 (60) | 0.151 |
Blood loss, ml | 450 (250–750) | 350 (250–575) | 725 (312–1150) | 0.107 |
Lactate before, mmol/l | 1.3 (0.8–2.6) | 1.4 (1–2.6) | 1.1 (0.7–2.4) | 0.604 |
Lactate after, mmol/l | 1.4 (1.1–3.1) | 1.3 (0.9–2.9) | 2.8 (1.5–5.6) | 0.083 |
Urinary output, ml | 50 (0–100) | 50 (0–100) | 25 (0–162) | 0.734 |
Outcome | ||||
Ventilator days | 9 (4–18) | 10 (4–25) | 8 (3–14) | 0.494 |
LOS ICU, days | 10 (6–24) | 11 (6–33) | 9 (5–14) | 0.118 |
All-cause 30-day mortality | 16 (46) | 7 (28) | 9 (90) | 0.002 |
Adjusted mortality | 7 (20) | 1 (4) | 6 (60) | 0.001 |