Table 2 Intraoperative stress marker levels
Variables | Timepoints | Control group (n = 24) | Ropivacaine group (n = 23) | Low DEX + ropivacaine group (n = 24) | Medium DEX + ropivacaine group (n = 25) | High DEX + ropivacaine group (n = 24) | P value |
|---|---|---|---|---|---|---|---|
Cor (μmol/L) | T0 | 317 ± 44 | 327 ± 52 | 308 ± 41 | 307 ± 44 | 322 ± 39 | 0.454 |
T1 | 396 ± 34 | 359 ± 34 | 339 ± 19 | 304 ± 17 | 283 ± 16 | 0.001 | |
T2 | 405 ± 34 | 348 ± 17 | 341 ± 17 | 301 ± 21 | 285 ± 18 | 0.005 | |
T3 | 407 ± 25 | 359 ± 23 | 337 ± 16 | 307 ± 26 | 281 ± 21 | 0.002 | |
NE (pg/ml) | T0 | 309 ± 11 | 301 ± 13 | 302 ± 18 | 306 ± 14 | 302 ± 14 | 0.145 |
T1 | 351 ± 8 | 314 ± 15 | 305 ± 15 | 305 ± 8 | 267 ± 12 | 0.001 | |
T2 | 356 ± 10 | 326 ± 17 | 308 ± 18 | 292 ± 15 | 263 ± 10 | 0.001 | |
T3 | 358 ± 10 | 329 ± 16 | 315 ± 17 | 263 ± 10 | 273 ± 13 | 0.001 | |
E (pg/ml) | T0 | 80.2 ± 2.1 | 79.8 ± 1.6 | 79.5 ± 1.6 | 80.1 ± 1.7 | 80.0 ± 1.4 | 0.584 |
T1 | 89.2 ± 2.0 | 83.7 ± 1.2 | 80.8 ± 1.6 | 79.8 ± 1.5 | 77.2 ± 1.8 | 0.001 | |
T2 | 89.4 ± 1.8 | 86.0 ± 0.7 | 83.4 ± 0.9 | 79.9 ± 1.6 | 77.5 ± 1.6 | 0.001 | |
T3 | 88.7 ± 1.5 | 86.1 ± 1.0 | 83.3 ± 0.9 | 79.8 ± 1.4 | 77.3 ± 1.9 | 0.001 | |
IL-6 (pg/ml) | T0 | 18.4 ± 0.8 | 17.8 ± 0.9 | 18.3 ± 0.7 | 17.9 ± 0.7 | 18.1 ± 0.6 | 0.155 |
T1 | 26.3 ± 2.2 | 24.9 ± 1.0 | 23.4 ± 1.0 | 17.9 ± 0.7 | 16.2 ± 0.8 | 0.002 | |
T2 | 27.0 ± 1.4 | 25.3 ± 0.9 | 23.5 ± 0.9 | 18.2 ± 0.9 | 16.0 ± 1.0 | 0.002 | |
T3 | 27.2 ± 1.5 | 26.1 ± 1.6 | 23.0 ± 0.9 | 18.3 ± 0.8 | 16.0 ± 1.1 | 0.001 | |
Glu (mmol/L) | T0 | 4.52 ± 0.45 | 4.51 ± 0.45 | 4.75 ± 0.49 | 4.54 ± 0.56 | 4.7 ± 0.55 | 0.092 |
T1 | 5.77 ± 0.31 | 5.37 ± 0.46 | 4.98 ± 0.46 | 4.62 ± 0.15 | 4.03 ± 0.29 | 0.003 | |
T2 | 5.98 ± 0.55 | 5.65 ± 0.32 | 5.32 ± 0.25 | 4.86 ± 0.46 | 4.04 ± 0.20 | 0.004 | |
T3 | 5.90 ± 0.46 | 5.60 ± 0.27 | 5.27 ± 0.27 | 4.97 ± 0.44 | 4.07 ± 0.18 | 0.004 |