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Table 3 Effectiveness outcomes

From: The analgesic efficacy of ultrasound-guided transversus abdominis plane block for retroperitoneoscopic renal surgery: a randomized controlled study

 

Group C (n = 51)

Group T (n = 52)

Estimated effects (95% CI) a

P value

Opioid consumption during surgery

 Sufentanil, μg

20 (15, 38)

23 (20, 30)

Median D = 0 (−5, 5)

0.685

 Remifentanil, μg

600 (502, 794) (n = 33)

607 (428, 818) (n = 39)

Median D = 0 (− 119, 120)

0.977

 Morphine equivalent dose, mg

35.0 (18.0, 49.6)

40.3 (20.9, 59.0)

Median D = 4.4 (−3.6, 13.4)

0.281

 Morphine equivalent dose, mg/kg

0.58 (0.29, 0.77)

0.59 (0.30, 0.87)

Median D = 0.05 (−0.06, 0.18)

0.326

Opioid consumption within 24 h after surgery

 Sufentanil, μg

33 (23, 65)

40 (24, 80)

Median D = 4 (−4, 14)

0.311

 Morphine equivalent dose, mg

10.8 (7.8, 21.7)

13.2 (8.0, 26.6)

Median D = 1.2 (−1.3, 4.8)

0.311

 Morphine equivalent dose, mg/kg

0.16 (0.12, 0.31)

0.19 (0.12, 0.39)

Median D = 0.02 (−0.02, 0.07)

0.252

Laparoscopic partial nephrectomy

(n = 27)

(n = 28)

  

 Intraoperative MED, mg

41.2 (14.0, 49.6)

38.0 (19.0, 60.4)

Median D = 4.4 (−10.6, 16.6)

0.480

 Postoperative MED within 24 h, mg

10.1 (7.4, 19.8)

17.7 (8.4, 26.1)

Median D = 3.1 (−0.3, 10)

0.070

Laparoscopic radical nephrectomy

(n = 24)

(n = 24)

  

 Intraoperative MED, mg

30.0 (19.2, 52.7)

40.7 (26.9, 53.8)

Median D = 5.5 (−6.8, 18.7)

0.370

 Postoperative MED within 24 h, mg

14.5 (8.2, 25.0)

10.6 (8.0, 27.8)

Median D = -0.9 (−6.0, 4.4)

0.773

Data from the PCA system

 Number of required bolus

4 (1, 10)

6 (1, 15)

Median D = 1 (−1, 4)

0.335

 Number of administered bolus

3 (1, 10)

5 (1, 12)

Median D = 1 (−1, 3)

0.338

 Time to first required bolus, hour b

1.7 (0.4, 3.0)

6.0 (2.8, 9.2)

HR = 1.46 (0.93, 2.30)

0.088

Data of rescue analgesia within 24 h after surgery

 Percentage of rescue analgesics

12 (23.5%)

19 (36.5%)

OR = 0.53 (0.23, 1.26)

0.153

 Frequency of rescue analgesics

2 (1, 3)

1 (1, 4)

Median D = 0 (−1, 0)

0.306

 Time to first rescue analgesics, hour b

21.0 (14.4, 27.6)

25.0 (19.3, 30.7)

HR = 1.08 (0.52, 2.24)

0.843

  1. Data are presented as median (interquartile range) or number of patient (%), unless otherwise indicated
  2. D difference, MED morphine equivalent dose, PCA patient controlled analgesia
  3. aCalculated as Group T vs. or minus Group C
  4. bData were analysed by Kaplan-Meier analysis and compared by log-rank test; the results are presented as the median (95% confidence interval)
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BMC Anesthesiology

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