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Table 3 Independent risk factors for postoperative AKI

From: Preoperative hypoalbuminemia was associated with acute kidney injury in high-risk patients following non-cardiac surgery: a retrospective cohort study

 

Univariate Logistic model a

Multivariate Logistic model b

OR (95% CI)

P value

OR (95% CI)

P value

Age (y)

1.022 (1.010–1.034)

< 0.001

1.018 (1.004–1.033)

0.013

History of chronic kidney disease

4.756 (2.023–11.180)

< 0.001

–

–

Sepsis

1.869 (1.013–3.451)

0.046

–

–

Radiocontrast exposure c

1.797 (1.091–2.961)

0.021

1.843 (1.031–3.293)

0.039

Baseline creatinine (umol/L) d

1.011 (1.005–1.017)

< 0.001

1.016 (1.008–1.025)

< 0.001

Preoperative Hb (g/L) e

0.990 (0.983–0.997)

0.004

–

–

Preoperative albumin < 37.5 g/L e

2.277 (1.624–3.194)

< 0.001

1.892 (1.238–2.891)

0.003

ASA classification

1.966 (1.472–2.625)

< 0.001

1.719 (1.193–2.477)

0.004

Open surgery

1.792 (1.213–2.650)

0.003

–

–

Emergency surgery

2.284 (1.349–3.869)

0.002

  

General surgery f

1.582 (1.133–2.208)

0.007

–

–

Duration of surgery (every 1 h increase)

1.047 (0.976–1.124)

0.202

–

–

Intraoperative use of vasopressors g

1.660 (1.146–2.404)

0.007

1.680 (1.065–2.648)

0.026

Non-renal SOFA within 24 h ICU admission

1.133 (1.044–1.230)

0.003

–

–

  1. ASA American Society of Anesthesiologists, CI confidence interval, Hb hemoglobin, OR odds ratio, SOFA sequential organ failure assessment score
  2. a Perioperative variables with P < 0.10 in the univariate analyses by independent samples t test, Mann-Whitney U test, chi-squared test, or Fisher’s exact test were included, except preoperative BNP, duration of anesthesia, and postoperative minimal Hb before AKI because of collinearity
  3. b Backward: LR
  4. c Including patients who had radiocontrast exposure within 7 days before surgery
  5. d Determined by the minimal value of serum creatinine measured within 3 months before admission and in hospital before surgery; if neither value was available, the modification of diet in renal disease formula was adopted to estimate the baseline serum creatinine according to the Kidney Disease Improving Global Outcomes guideline
  6. e Measured within 3 days before surgery
  7. f Abdominal surgery, such as gastrointestinal, hepatobiliary, and pancreatic surgery
  8. g Including use of phenylephrine, norepinephrine, epinephrine, and dopamine
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BMC Anesthesiology

ISSN: 1471-2253

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