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Table 3 Duration of Surgery, Anesthesia, ICU and hospital stay, Complications of surgery

From: Effects of a metabolic optimized fast track concept (MOFA) on bowel function and recovery after surgery in patients undergoing elective colon or liver resection: a randomized controlled trial

 

Control group

MOFA group

P value

Duration of surgery

 [min]

  All

190 (92,157, 265, 529) [50]

215 (89, 158, 310, 560) [50]

0.425

  Colon

175 (92, 150, 203, 293) [30]

206 (89, 153, 268, 482) [30]

0.240

  Liver

235 (130, 169, 397, 528) [20]

221 (92, 166, 336, 560) [20]

0.654

Duration of anesthesia

 [min]

  All

276 (180, 239, 355, 620) [50]

300 (176, 245, 418,632) [50]

0.491

  Colon

262 (180, 238, 309, 390) [30]

289 (187, 243, 361, 570) [30]

0.578

  Liver

335 (196, 237, 537, 620) [20]

323 (176, 245, 465, 632) [20]

0.186

Intraoperative blood loss

 [ml]

  All

175 (0, 30, 1025, 3000) [50]

400 (0, 30, 950, 3000) [49]

0.775

  Colon

50 (0, 30, 200, 1150) [30]

30 (0, 20, 100, 3000) [29]

0.399

  Liver

1100 (100, 613, 1438, 3000) [20]

950 (50, 525, 1950, 2820) [20]

0.909

Need for transfusionb [no]

 All

10 (20.0) [50]

6 (12.0) [50]

0.414

 Colon

2 (6.7) [30]

1 (3.3) [30]

1.000

 Liver

8 (40.0) [20]

5 (25.0) [20]

0.501

Transfusion products

 PRBC [units]

4.0 (2.0, 2.5, 5.0, 8.0) [9]

2.5 (1.0, 2.0, 4.0, 6.0) [8]

0.288

 FFP [units]

4.0 (2.0, 2.0, 5.25, 9.0) [6]

3.0 (2.0,2.0, 4.0, 4.0) [4]

n.a.

Cumulative fluid therapy

 Crystalloids [ml]

  All

2500 (500, 1375, 3500, 5900) [50]

1750 (0, 1100, 2500, 6500) [49]

0.054

  Colon

1500 (500, 1000, 2500, 5500) [30]

1500 (0, 1000, 2250, 6500) [29]

0.758

  Liver

3500 (2000, 3000, 4000, 5900) [20]

2263 (0, 1500, 3500, 5300) [20]

0.004

 Colloids [ml]

  All

500 (0, 500, 1500, 2500) [50]

1000 (0, 500, 1500, 3000) [49]

0.043

  Colon

500 (0, 0, 1000, 2000) [30]

500 (0, 500, 1000, 3000) [29]

0.005

  Liver

1500 (500, 500, 1500, 2500) [20]

1500 (0, 500, 2000, 3000) [20]

0.504

Hospital length of stay [days]

 All

8.0 (6.0, 8.0, 9.0, 20.0) [37]

8.0 (6.0, 8.0, 9.0, 20.0) [43]

0.466

 Colon

8.0 (6.0, 7.0, 10.0, 30.0) [23]

8.0 (6.0, 7.0, 9.0, 12.0) [27]

0.651

 Liver

8.0 (6.0, 8.0, 9.0, 20.0) [14]

9.0 (7.0, 8.8, 10.3, 13.0) [16]

0.860

ICU length of stay [hours]

 All

34 (21, 23, 49, 67) [14]

27 (12, 20, 45, 80) [15]

0.237

 Colon

49 [1]

30 (12, 13, 43, 44) [4]

n.a.

 Liver

25 (21, 22, 49, 67) [13]

27 (18, 21, 45, 88) [11]

0.558

Postoperative surgical complicationsa [no.]

 Bleeding

0 (0.0) [50]

1 (2.0) [50]

1.000

 Insufficiency of

4 (8.0) [50]

0 (0.0) [50]

0.118

anastomosis

 Wound infection

3 (6.0) [50]

0 (0.0) [50]

0.242

 Non-infective wound

1 (2.0) [50]

1 (2.0) [50]

1.000

complication

 Biliary fistula

0 (0.0) [50]

0 (0.0) [50]

n.a.

 Reoperation

4 (8.0) [50]

0 (0.0) [50]

0.118

 other

2 (4.0) [50]

2 (4.0) [50]

1.000

In-hospital death [no.]

1 (2.0) [50]

0 (0.0) [50]

1.000

  1. Values are given as mean ± standard deviation, median (minimum, 25% percentile, 75% percentile, maximum) or absolute number (percentage) as appropriate. Number of analyzed patients can be found in brackets. Statistical significance was considered to be at two-sided p < 0.05. Differences between groups were tested using a Student’s t-test or Mann-Whitney U test as appropriate. Frequencies were analyzed using Chi-square or Fisher’s Exact test, as appropriate. FFP Fresh frozen plasma, ICU Intensive care unit, MOFA Metabolic optimized fast track concept, PRBC packed red blood cells. a: Postoperative surgical complications are provided during whole hospital stay or until dropout. b: need for transfusion is given during whole hospital stay or until dropout
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BMC Anesthesiology

ISSN: 1471-2253

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