Fig. 5From: Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathwayBlockade of the PI3K/Akt/mTOR pathway reduced the anti-inflammatory activity of dexmedetomidine Western blot measurements of IL-6, IL-8 and TNF- α from cortical and hippocampal samples of rats in the DEX and DEX + LY294002 groups (mean ± SD, n = 5 per group, t test). *p < 0.05 vs DEX groupBack to article page