The tidal volume challenge improves the reliability of dynamic preload indices during robot-assisted laparoscopic surgery in the Trendelenburg position with lung-protective ventilation

Table 3 Prediction of Fluid Responsiveness based on the ROC Curves of Various Indices

	AUC (95%CI)	P-value	Cut-off value,%	Sensitivity (95% CI)	Specificity (95% CI)	Grey zone (%)	Patients in the grey zone number (%)
PPV₆	0.69 (0.52–0.83)	0.036	> 6	54 (33–74)	79 (49–95)	3.2 to 7.8	22 (58)
SVV₆	0.56 (0.39–0.72)	0.563	–	–	–
PPV₈	0.85 (0.70–0.95)	< 0.0001	> 7	79 (58–93)	79 (49–95)	6.2 to 8.6	10 (26)
SVV₈	0.77 (0.61–0.89)	0.0003	> 5	67 (45–84)	79 (49–95)	2.7 to 6.3	21 (55)
ΔPPV_6–8	0.95 (0.83–0.99)	< 0.0001	> 1	92 (73–99)	86 (57–98)	1 to 1.3	9 (24)
ΔSVV_6–8	0.76 (0.60–0.89)	0.0006	> 2	46 (26–67)	100 (77–100)	−1.5 to 1.4	21 (55)
%ΔPPV_6–8	0.87 (0.72–0.96)	< 0.0001	> 25	83 (63–95)	79 (49–95)	20.5 to 46	12 (32)
%ΔSVV_6–8	0.71 (0.55–0.85)	0.02	> 16.7	67 (45–85)	79 (49–95)	−32 to 95	27 (71)

ROC Receiver operating characteristic, AUC Area under the curve, CI Confidence interval, PPV₆ Pulse pressure variation during tidal volume at 6 ml/kg predicted body weight (PBW), SVV₆ Stroke volume variation during tidal volume at 6 ml/kg PBW, PPV₈ Pulse pressure variation during tidal volume at 8 ml/kg PBW, SVV₈ Stroke volume variation during tidal volume at 8 ml/kg PBW, ΔPPV_6–8 Change in value of pulse pressure variation after tidal volume challenge, ΔSVV_6–8 Change in value of stroke volume variation after tidal volume challenge, %ΔPPV_6–8 Percentage change in value of pulse pressure variation after tidal volume challenge, %ΔSVV_6–8 Percentage change in value of stroke volume variation after tidal volume challenge

ISSN: 1471-2253