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Table 3 Intraoperative fluid and vasoactive medications in patients undergoing open right hepatectomy

From: Impact of a goal directed fluid therapy algorithm on postoperative morbidity in patients undergoing open right hepatectomy: a single centre retrospective observational study

  GDFT group (n = 26) Usual care group (n = 32) Effect Size p-value
Crystalloid therapy
 Number of patients 26 (100%) 32 (100%)   >.99
 Total volume (mls) 1250 (1000 to 2025) 2000 (1725 to 3150) -799 (−1414 to − 186)b 0.007
Colloid therapy (excluding blood)
 Number of patients 17 (65%) 18 (56%)   0.59
 Total volume (mls) 500 (200 to 1000) 750 (500 to 1000) −105 (− 173.7 to 382.8) 0.41
Colloid type
 4% albumen (no of patients) 11 (42%) 15 (47%)   0.79
 Total volume (mls) 1000 (500:1000) 1000 (500:1000)   
 20% albumen (no of patients) 6 (23%) 3 (9%)   0.27
 Total volume (mls) 200 (100:200) 200 (100:200)   
 Total fluids (including colloids, crystalloids and blood) (mls) 2000 (1175 to 2700) 2750 (2000 to 4000) −729 (−1462 to −3.03)a 0.026
 Blood transfusion (number of patients) 3 (11.5%) 2 (6.2%)   0.4
 Total volume (ml) 465 (465:1000) 1275 (1275:1400)   
 Urine output (ml) 220 (155 to 300) 320 (195 to 485)   0.022
 Blood loss (ml) 400 (300 to 950) 400 (300 to 750) 17.0 (−201 to 235)b 0.61
 Fluid balance 1215 (613 to 1680) 2095 (1330 to 3608) −921 (−1646 to −196)b 0.005
 Number of patients receiving a vasoactive medication 20 (77%) 29 (91%) 0.23 (0.04 to 1.1) c 0.12
 Metaraminol use (number of patients) 6 (23%) 23 (72%) 0.12 (0.04 to 0.37)c < 0.001
 Metaraminol (mg) 0 (0–1) 3 (0–9) −3.64 (−5.82 to −1.46)b < 0.005
 Ephedrine/dopamine use (number of patients) 3 (12%) 8 (25%) 0.39 (0.10 to 1.61)c 0.31
 Epinephrine (mg) 0 (0–0) 0 (0–8) 4.56 (−9.50 to 0.38)b 0.08
 Noradrenaline use (number of patients) 15 (46%) 9 (28%) 3.49 (1.23 to 9.47) c 0.03
 Noradrenaline (ug) 390 (0 to 870) 0 (0 to 353) 1.67 (− 325 to 662)b 0.10
  1. aEffect size reported as incidence rate ratio. bEffect size reported as difference in means cEffect size reported as odds ratio
  2. Data presented as median (interquartile range), or number (proportion)