Table 2 Characteristics of the 200 kidney-transplant recipients at the admission in ICU and during ICU stay
Characteristics | Total N = 200 | Survivors N = 160 | In-hospital death N = 40 | p |
|---|---|---|---|---|
Time since kidney transplantation (months) | 40 [5–119] | 37 [4–118] | 54 [12–122] | 0.14 |
Causes of admission (n, %) | ||||
Acute respiratory failure | 55 (27.5) | 42 (26.3) | 13 (32.5) | 0.43 |
Septic shock | 53 (26.5) | 42 (26.3) | 11 (27.5) | 0.84 |
Unplanned surgery | 46 (23) | 40 (25) | 6 (15) | 0.21 |
Cardiogenic shock | 18 (9) | 12 (7.5) | 6 (15) | 0.21 |
Acute neurological condition | 12 (6) | 9 (5.6) | 3 (7.5) | 0.71 |
Acute kidney injury | 10 (5) | 10 (6.3) | 0 (0) | 0.22 |
Others | 6 (3) | 5 (3.1) | 1 (2.5) | 1.00 |
Sepsis at the admission (n, %) | ||||
Overall | 114 (57) | 89 (55.6) | 25 (63) | 0.48 |
Lung | 57 (50) | 47 (52.9) | 10 (40) | 0.70 |
Urinary | 26 (22.8) | 23 (25.8) | 3 (7.5) | 0.30 |
Peritonitis | 24 (21) | 14 (15.7) | 10 (25) | 0.01 |
Others | 7 (6.1) | 5 (5.1) | 2 (1.4) | 0.64 |
Organ failures (n, %) | ||||
SOFA score | 6 [4–8] | 6 [4–8] | 8 [7–10] | < 0.001 |
SAPS2 score | 50 [39–63] | 48 [37–59] | 67[57–77] | < 0.001 |
Acute kidney injury (KDIGO) | ||||
stage 1 | 49 (24.5) | 42 (26.3) | 7 (17.5) | |
stage 2 | 8 (4) | 6 (3.8) | 2 (5) | |
stage 3 | 113 (56.5) | 86 (53.8) | 27 (67.5) | 0.008 |
Renal replacement therapy | 103 (51.5) | 76 (47.5) | 27 (67.5) | 0.03 |
Mechanical ventilation | 107 (53.5) | 78 (48.8) | 29 (72.5) | 0.008 |
Vasopressive drugs | 97 (48.5) | 68 (42.5) | 29 (72.5) | 0.001 |
Normalized prothrombin time < 50% | 11 (5.5) | 5 (3.1) | 6 (15) | 0.01 |
RBC transfusion | 142 (71) | 109 (68.1) | 33 (82.5) | 0.08 |
Immunosuppressive regimen (n, %) | ||||
No change | 45 (22.5) | 45 (28.1) | 0 (0) | 0.02 |
Increased dose of steroids | 136 (68) | 100 (62.5) | 36 (90) | 0.2 |
Withdrawal of CNI | 40 (20) | 25 (15.6) | 15 (37.5) | 0.004 |
Withdrawal of antimetabolites | 61 (30) | 48 (30) | 13 (32.5) | 0.85 |