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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Desflurane impairs hippocampal learning on day 1 of exposure: a prospective laboratory study in rats

Fig. 3

IA latencies. (a) IA latencies on day 1 were significantly declined in the 1.2 MAC desflurane (n = 17, 104 ± 34 s) (post hoc Tukey’s, *P = 0.004), but not in the 0.7 MAC desflurane group (n = 17, 206 ± 39 s) (post hoc Tukey’s, P = 0.362) compared with the control (n = 17, 273 ± 31 s). (b) IA latencies were not declined on day 3 (control [n = 16], 264 ± 38 s; desflurane [n = 16], 229 ± 32 s) and day 7 (control [n = 15], 159 ± 35 s; desflurane [n = 15], 160 ± 44 s) (two-way ANOVA, group, F [1,90] = 5.426, P = 0.022; day, F [2,90] = 0.052, P = 0.417; group x day, F [1,90] = 3.263, P = 0.043, post hoc Sidak’s multiple comparison test, day 3, control vs. desflurane, P = 0.861; day 7, control vs. desflurane, P > 0.999). Each rat was tested only once. The same data are used for day 1 in (a) and (b). Data are presented as mean ± SEM

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