Effects of terlipressin infusion during hepatobiliary surgery on systemic and splanchnic haemodynamics, renal function and blood loss: a double-blind, randomized clinical trial

Table 2 Hemodynamic variables

Variables		Group T N = 25	Group C N = 25	P value
HR (beat/m.)	Baseline	77.3 ± 7.9	80.1 ± 7.7	0.22
	Intraoperative	79.6 ± 14.4	84.5 ± 14.5	0.24
	Postoperative	85.2 ± 11.3*	90.8 ± 12*	0.09
MAP (mm HG)	Baseline	85.8 ± 8.7	89.4 ± 12.8	0.25
	Intraoperative	88.7 ± 7.2	83.9 ± 6.98	0.02^¥
	Postoperative	80.2 ± 12.3	86.1 ± 9.9	0.07
CVP (mm Hg)	Baseline	14.0 (8–20)	14.0 (8–22)	0.34
	Intraoperative	12.4 (8.3–19.2)	12.6 (7.1–21.4)	0.84
	Postoperative	9.0 (2–12)”	8.0 (5–21)”	0.60
CI (L/min/m²)	Baseline	3.6 ± 0.9	3.4 ± 1.1	0.43
CI (L/min/m²)	Intraoperative	3.1 ± 0.3*	3.3 ± 0.6	0.15
SVV %	Baseline	7.4 ± 3.90	9.2 ± 2.98	0.08
SVV %	Intraoperative	10.6 ± 2.17*	11.0 ± 2.14*	0.50
SVR (dyne.s/cm⁵)	Baseline	1030.2 ± 318.1	1021.8 ± 285.2	0.92
SVR (dyne.s/cm⁵)	Intraoperative	1144.9 ± 221.0*	1007.2 ± 232.4	0.04^¥
Need for inotropic support, no. of patients		1(4%)	3(12%)	0.30
Inotropic score		5 (5–5)	10(5–10)	0.32

Data are presented as mean ± SD or median (range). HR heart rate; MAP mean arterial pressure; CI cardiac index; SVV stroke volume variation; SVR systemic vascular resistance. P-value <0.05 was considered statistically significant. (*) significant difference in comparison to the baseline value within the same group. (^¥) significant difference between the two groups. The inotropic score is calculated as follows: One point was assigned for each mcg/kg/min of dobutamine, and 1 point was assigned for each 10 ng/kg/min of norepinephrine)

ISSN: 1471-2253