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Table 2 Univariate and multivariable predictors for composite 90-day major complications after cardiovascular surgery

From: The relationship of preoperative estimated glomerular filtration rate and outcomes after cardiovascular surgery in patients with normal serum creatinine: a retrospective cohort study

Predictor

Univariatea

Multivariableb

OR (95% CI)

P value

OR (95% CI)

P value

eGFRc

1.259 (1.176–1.347)

<  0.001

1.232 (1.148–1.322)

<  0.001

Age

1.028 (1.017–1.038)

<  0.001

  

Body mass index (kg/m2)

0.965 (0.931–1.000)

0.052

  

EuroSCORE (logistic)

1.070 (1.054–1.086)

<  0.001

  

Hematocrit (%)

0.908 (0.887–0.929)

<  0.001

0.963 (0.937–0.989)

0.005

Bilirubin, total (mg/dL)

1.514 (1.228–1.868)

<  0.001

1.368 (1.090–1.717)

0.007

Serum albumin (g/dL)

0.278 (0.219–0.352)

<  0.001

0.363 (0.276–0.478)

<  0.001

Uric acid (mg/dL)

1.101 (1.032–1.175)

0.003

  

C-reactive protein (mg/dL)

1.249 (1.175–1.327)

<  0.001

  

LVEF (%)

0.980 (0.970–0.990)

<  0.001

  

Congestive heart failure

2.077 (1.427–3.023)

<  0.001

  

Peripheral vascular disease

1.801 (1.295–2.538)

0.001

1.882 (1.295–2.736)

0.001

Liver disease

1.753 (1.094–2.809)

0.020

  

Dyslipidemia

0.719 (0.547–0.944)

0.018

  

Smoker, current

1.622 (1.149–2.290)

0.001

1.561 (1.126–2.165)

0.008

ACEI or ARB

1.285 (1.016–1.625)

0.036

  

Insulin

1.989 (1.368–2.890)

<  0.001

  

Use of diuretics

2.084 (1.643–2.643)

<  0.001

1.562 (1.198–2.037)

0.001

  1. a all variables were initially entered into a full multivariable regression analysis and were removed individually to assess each variable’s contribution to the model using backward elimination process with a P value cutoff of 0.05
  2. b final model, Hosmer-Lemeshow test; P = 0.738, C statistic = 0.724
  3. c for each 10 mL/min/1.73 m2 decrease
  4. OR Odds Ratio, CI confidence interval, eGFR estimated glomerular filtration rate, EuroSCORE European System for Cardiac Operative Risk Evaluation, LVEF Left ventricle ejection fraction, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker