Table 1 Clinical characteristics of critically ill patients presented to the Six Affiliated Hospital, Sun Yat-sen University from 2016 to 2017
Total | Control | Hypophosphatemia | P | |
|---|---|---|---|---|
Age (years), mean ± SD | 62.41 ± 17.06 | 62.26 ± 17.32 | 62.58 ± 16.78 | 0.77 |
Male (%) | 618 (65. 3%) | 280 (63.6%) | 338 (67.1%) | 0.25 |
APACHE II scores, mean ± SD | 18.78 ± 7.56 | 17.02 ± 7.43 | 25.64 ± 12.31 | 0.00 |
Reason for admission (%) | ||||
Sepsis and sepsis shock | 281 (29.7%) | 125 (28.3%) | 156 (31.0%) | 0.37 |
Postoperative | 333 (35.2%) | 170 (38.5%) | 163 (32.3%) | 0.05 |
Hemorrhagic shock | 64 (6.8%) | 32 (7.3%) | 32 (6.3%) | 0.59 |
Respiratory failure | 82 (8.7%) | 38 (9.4%) | 44 (8.7%) | 0.94 |
Cardiovascular disease | 66 (7.0%) | 28 (6.3%) | 38 (7.5%) | 0.47 |
Cerebral disease | 41 (4.3%) | 21 (4.8%) | 20 (4.0%) | 0.56 |
Severe acute pancreatitis | 8 (0.8%) | 2 (0.5%) | 6 (1.2%) | 0.22 |
Others | 71 (7.5%) | 26 (5.9%) | 45 (8.9%) | 0.08 |
Underlying disease | ||||
Cancer | 587 (62.1%) | 286 (64.7) | 301 (59.7%) | 0.12 |
Hypertension | 181 (19.1%) | 70 (15.8%) | 111 (22.0%) | 0.10 |
Diabetes mellitus | 91 (10%) | 40 (9.0%) | 51 (10.1%) | 0.58 |
Coronary heart disease | 49 (5.2%) | 23 (5.2%) | 26 (5.2%) | 0.98 |
Chronic renal insufficiency | 74 (7.9%) | 27 (6.1%) | 47 (9.3%) | 0.06 |
Chronic obstructive pulmonary disease | 30 (3.2%) | 12 (2.7%) | 18 (3.5%) | 0.45 |
Medications (%) | ||||
Insulin | 59 (6.3%) | 25 (5.7%) | 34 (6.8%) | 0.49 |
Furosemide | 22 (2.3%) | 7 (1.6%) | 15 (3.0%) | 0.16 |
Glucocorticoid | 24 (2.5%) | 8 (1.8%) | 16 (3.2%) | 0.18 |
Nutrition (%) | ||||
Parenteral | 261 (27.6%) | 120 (27.1%) | 141 (28.0%) | 0.78 |
Enteral | 138 (14.6%) | 70 (15.8%) | 68 (13.5%) | 0.39 |
Parenteral+ Enteral | 240 (25.4%) | 104 (23.5%) | 136 (26.8%) | 0.22 |
No nutrition support therapy | 307 (32.5%) | 148 (33.5%) | 159 (31.5%) | 0.52 |
Albumin (g/L), median (IQR) | 31.2 (25.9, 36.8) | 32.7 (27.3, 38.8) | 30.0 (25.2, 35.0) | 0.00 |
Calcium (mM), median (IQR) | 1.99 (1.84, 2.14) | 1.98 (1.84, 2.13) | 2.00 (1.84, 2.15) | 0.37 |
Potassium (mM), median (IQR) | 3.9 (3.5, 4.3) | 4.0 (3.6, 4.3) | 3.8 (3.5, 4.3) | 0.00 |
Creatinine (μM), median (IQR) | 76.0 (54.0,124.0) | 75.0 (55.0,113.0) | 77.5 (52.5, 132.0) | 0.63 |
Phosphorus (mM), median (IQR) | 0.77 (0.55, 1.03) | 1.05 (0.92,1.24) | 0.56 (0.43, 0.67) | 0.00 |
GFR (ml/min1.73m2) | 76.36 ± 37.55 | 76.95 ± 36.35 | 75.84 ± 38.60 | 0.65 |