Effects of intravenous infusion of lidocaine and dexmedetomidine on inhibiting cough during the tracheal extubation period after thyroid surgery

Table 3 MAP and HR change

Variables	LIDO group	DEX group	CON group	P value
Variables	(n = 60)	(n = 60)	(n = 60)	P value
MAP (mmHg)
Before induction	86.9 ± 12.6	83.6 ± 10.4	87.6 ± 13.4	0.167
During tracheal extubation	84.8 ± 14.4	88.2 ± 14.5	101.4 ± 13.3^*	0.000
5 min after tracheal extubation	91.7 ± 16.5	90.8 ± 13.1	104.7 ± 15.7^*	0.000
HR (beat/min)
Before induction	79.8 ± 10.4	83.5 ± 13.4	83.6 ± 15.3	0.198
During tracheal extubation	80.7 ± 12.4	79.4 ± 8.1	95.3 ± 13.6^*	0.000
5 min after tracheal extubation	86.6 ± 13.8	85.2 ± 11.6	101.1 ± 15.6^*	0.000

Categorical variables were presented as the mean ± standard deviation for all of the patients, with 60 cases in each group. LIDO group, iv. lidocaine; DEX group, iv. dexmedetomidine; CON group, iv. equal volume normal saline. MAP, mean arterial pressure; HR, heart rate. Compared with the LIDO group and the DEX group, both MAP and HR were significantly increased in the CON group during tracheal extubation and 5 min after tracheal extubation (^*P = 0.000)

ISSN: 1471-2253