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Table 2 Baseline characteristics

From: Cardioprotective effect of remote ischemic preconditioning with postconditioning on donor hearts in patients undergoing heart transplantation: a single-center, double-blind, randomized controlled trial

 

RIPC+RIPostC (n = 60)

Control (n = 60)

P value

Demographics

 Age (years)

46.5 ± 16.2

47.1 ± 12.4

0.983

 Male

45 (75.0%)

44 (73.3%)

0.835

 BMI

21.6 ± 3.7

21.4 ± 3.2

0.990

Distribution of primary diseases

 Coronary heart diseases

10(16.7%)

9(15%)

0.803

 Cardiomyopathy

   

  Dilated cardiomyopathy

29(48.3%)

32(53.3%)

0.584

  Hypertrophic cardiomyopathy

5(8.3%)

7(11.7%)

0.543

  Restrictive cardiomyopathy

3(5%)

3(5%)

1

  ARVC

6(10%)

3(5%)

0.488

  Alcoholic cardiomyopathy

1(1.7%)

1(1.7%)

1

  Peripartum cardiomyopathy

0

1(1.7%)

1

 Noncompaction of ventricular myocardium

2(3.3%)

1(1.7%)

1

 Valvular heart disease

3(5.0%)

2(3.3%)

1

 Behcet disease

1(1.7%)

0

1

 Myocarditis

0

1(1.7%)

1

Risk factors and comorbidities

 Hypertension

7 (11.7%)

6 (10%)

0.518

 Diabetes mellitus

13 (21.7%)

10 (16.7%)

0.487

 Hypercholesterolemia

12 (20%)

12 (20%)

1

 Previous myocardial infarction

6 (10%)

4 (6.7%)

0.509

 Previous stroke

6 (10%)

6 (10%)

1

 Previous atrial fibrillation

20 (33.3%)

20 (33.3%)

1

 Previous cardiac surgery

6 (10%)

8 (13.3%)

0.570

Cardiac status

 Left-ventricular ejection fraction (%)

   > 55%

4(6.7%)

3(5%)

1

  35–55%

8(13.3%)

12(20%)

0.327

   < 35%

47(78.3%)

45(75%)

0.666

  Previous pacemaker

18(30%)

16(26.7%)

0.685

Preoperative medication

 Warfarin

8(13.3%)

12(20%)

0.327

 β blocker

50(83.3%)

52(86.7%)

0.609

 Lipid-lowering agent

3(5%)

8(13.3%)

0.114

 ACE inhibitors or ARB

30(50%)

11(18.3%)

< 0.001

 Aldosterone receptor blocker

46(76.7%)

57(95%)

0.803

 Digitalis

16(26.7%)

49(81.7%)

< 0.001

 Nitrates

5(8.3%)

12(20%)

0.670

 Anti-diabetic drugs

6(10%)

8(13.3%)

0.570

 Inotropic drugs

23(38.3%)

46(76.7%)

< 0.001

  1. Data are mean ± SD or number (%)
  2. BMI body mass index, ARVC arrythmogenic right ventricular cardiomyopathy, ACE angiotensin converting enzyme, ARB angiotensin-II-receptor blocker, NYHA New York Heart Association, RIPC remote ischemic preconditioning, RIPostC remote ischemic postconditioning