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Table 2 Dosing of thiopental for procedural MRI sedation

From: Premedication with intranasal dexmedetomidine decreases barbiturate requirement in pediatric patients sedated for magnetic resonance imaging: a retrospective study

 

Group

Dexmedetomidine (DEX)

Thiopental (THIO)

 
 

n

median (IQR)

n

median (IQR)

p-value

Thiopental induction dose (mg/kg)

ALL

100

1.8 (1.2–2.3)

100

5.1 (4.6–6.1)

<  0.001

 

0–2 years

20

2.3 (1.8–2.8)

24

4.8 (4.0–6.6)

<  0.001

 

2–6 years

50

1.7 (1.3–2.2)

53

5.2 (4.7–6.1)

<  0.001

 

6–11 years

30

1.4 (0.9–2.0)

23

5.0 (4.7–5.7)

<  0.001

Thiopental cumulative dose (mg/kg/h)

ALL

100

4.4 (2.7–6.0)

100

12.4 (9.8–14.8)

<  0.001

 

0–2 years

20

5.2 (4.2–6.4)

24

11.8 (9.1–14.2)

<  0.001

 

2–6 years

50

4.4 (2.2–5.9)

53

11.8 (9.7–15.2)

<  0.001

 

6–11 years

30

3.5 (1.7–6.3)

23

13.4 (11.2–15.3)

<  0.001