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Table 2 Dosing of thiopental for procedural MRI sedation

From: Premedication with intranasal dexmedetomidine decreases barbiturate requirement in pediatric patients sedated for magnetic resonance imaging: a retrospective study

  Group Dexmedetomidine (DEX) Thiopental (THIO)  
  n median (IQR) n median (IQR) p-value
Thiopental induction dose (mg/kg) ALL 100 1.8 (1.2–2.3) 100 5.1 (4.6–6.1) <  0.001
  0–2 years 20 2.3 (1.8–2.8) 24 4.8 (4.0–6.6) <  0.001
  2–6 years 50 1.7 (1.3–2.2) 53 5.2 (4.7–6.1) <  0.001
  6–11 years 30 1.4 (0.9–2.0) 23 5.0 (4.7–5.7) <  0.001
Thiopental cumulative dose (mg/kg/h) ALL 100 4.4 (2.7–6.0) 100 12.4 (9.8–14.8) <  0.001
  0–2 years 20 5.2 (4.2–6.4) 24 11.8 (9.1–14.2) <  0.001
  2–6 years 50 4.4 (2.2–5.9) 53 11.8 (9.7–15.2) <  0.001
  6–11 years 30 3.5 (1.7–6.3) 23 13.4 (11.2–15.3) <  0.001