Table 1 Overview of definitions of vasoplegia used and their criteria

Argenziano [1]

MAP < 70 mmHg

CI > 2.5 l·min^− 1·m^− 2

nor > 8 μg·min^− 1

5 min after CPB

Levin [2]

MAP < 50 mmHg and SVR < 800 dynes·s·cm^− 5

CI > 2.5 l·min^− 1·m^− 2

any vasopressor

CVP < 5 mmHg and PCWP < 10 mmHg

first 3 h after ICU arrival

Patarroyo [9]

SVR < 800 dynes·s·cm^− 5

CI > 2.5 l·min^− 1·m^− 2

≥ 2 vasopressors:

1. epi > 4 μg/min,

2. nor ≥4 μg/min,

3. dopa ≥5 μg· kg^− 1·min^− 1,

4. vasopressin ≥1 U/hr

6–48 h after ICU arrival

Unified definition

MAP < 50 mmHg

or SVR < 800 dynes·s·cm^− 5

CI > 2.5 l·min^− 1·m^− 2

nor > 200 ng·kg^− 1·min^− 1 or equivalent doses of other vasopressors:

epi ≥ 200 ng·kg^− 1·min^− 1;

dopa ≥30 μg·kg^− 1·min^− 1; phenyl ≥2 μg·kg^− 1·min^− 1; or vasopressin ≥0.08 U·min^− 1

first 48 h after ICU arrival