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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Increased expression of the Cbl family of E3 ubiquitin ligases decreases Interleukin-2 production in a rat model of peripheral neuropathy

Fig. 3

(a) Western blot analyses of c-Cbl, Cbl-b, c-Cbl (pY700), and phosphorylated Cbl-b levels at 1, 3, and 6 weeks after spinal nerve ligation. c-Cbl, Cbl-b, and c-Cbl (pY700) levels were significantly increased, and those of phosphorylated Cbl-b were significantly decreased at 3 and 6 weeks after spinal nerve ligation. (b) The level of ubiquitin conjugation in the spinal cord ipsilateral to the spinal nerve ligation peaked at 3 weeks. (c) Levels of phosphorylated and non-phosphorylated ZAP70 and PLC-γ1 were significantly decreased at 3 and 6 weeks after spinal nerve ligation

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BMC Anesthesiology

ISSN: 1471-2253

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