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Table 3 ROC statistics for miR-122 and serum bilirubin concentration over the course of disease and treatment

From: Increased circulating microRNA-122 is associated with mortality and acute liver injury in the acute respiratory distress syndrome

Test

AUC

Confidence interval

Significance level

miR-122

0.782

0.694–0.870

< 0.001

Bilirubin conc. on day 1

0.663

0.564–0.763

0.003

Bilirubin conc. on day 5

0.655

0.546–0.764

0.007

Bilirubin conc. on day 10

0.767

0.662–0.871

< 0.001

ALT activity on day 1

0.574

0.427–0.720

0.188

ALT activity on day 5

0.476

0.326–0.626

0.732

ALT activity on day 10

0.534

0.383–0.686

0.630

INR on day 1

0.551

0.412–0.690

0.470

INR on day 5

0.603

0.464–0.758

0.185

INR on day 10

0.684

0.561–0.808

0.010

  1. Area under curve, asymptotic confidence interval as well as asymptotic P- values are given for relative miR-122 expression, serum bilirubin concentration Alanine aminotransferase (ALT) activity in U/l, and International Normalized Ratio (INR) on day 1, 5, and 10