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Table 2 Time to develop predefined major abnormalities

From: Effects of acute ethanol intoxication in an ovine peritonitis model

 

Ethanol, n = 7

Control, n = 7

p (Log-rank)

MAP < 65 mmHg

8 [7–12]

14 [11–20]

0.03

SVRI < 1200 dyn·s/cm5·m2

11 [9–13]

14 [10–16]

0.19

Renal blood flow < ×  0.75a

9 [6–13]

13 [12–15]

0.05

Hourly UO < 0.5 mL/kg

10 [7–12]

13 [12–13]

0.01

pH < 7.25

8 [4–15]

15 [13–20]

0.05

BT increase > + 1.5 °Ca

10 [8–16]

11 [7–12]

0.54

PaO2/FIO2 ratio < 200

13 [11–15]

17 [13–20]

0.13

Brain LD < ×  0.8a

16 [13–16]

16 [13–19]

0.49

Brain MD LPR > 25

14 [10–16]

12 [8–14]

0.59

Death

16 [14–22]

20 [19–24]

0.11

  1. All data (hours) are presented as median [IQR]. a, compared with baseline (defined as the time of feces injection) values
  2. BT blood temperature, LD laser Doppler, LPR lactate pyruvate ratio, MAP mean arterial pressure, MD microdialysis, SVRI systemic vascular resistance index, UO urine output