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Table 1 Baseline characteristics of the four troponin-I groups

From: Association between troponin-I levels and outcome in critically ill patients admitted to non-cardiac intensive care unit with high prevalence of cardiovascular risk factors

Variables

Group I

<0.03ng/ml

N = 649

Group II

0.03 – 0.3ng/ml

N = 1572

Group III

0.3 – 3ng/ml

N = 750

Group IV

>3ng/ml

N = 397

P-value

Age, year, Mean ± SD

47.3 ± 21.1

55.2 ± 19.9

55.9 ±  20.6

58.4 ± 20.3

<0.0001

Gender, male, N (%)

429 (66.1)

991 (63.0)

478 (63.7)

267 (67.3)

0.31

APACHE II score, Mean ± SD

20.3 ± 8.6

23.0 ± 9

27.0 ± 9.3

29.7 ± 9.0

<0.0001

Glasgow Coma Scale, Mean ± SD

10.1 ± 4.3

10.1 ± 4.4

9 ± 4.7

8.0 ± 4.7

<0.0001

Admission diagnosis category, N (%)

 Respiratory

121 (18.6)

315 (20.0)

144 (19.2)

70 (17.6)

<0.0001

 Cardiovasculara

127 (19.6)

451 (28.7)

289 (38.5)

202 (50.8)

 Neurologic

69 (10.6)

89 (5.7)

35 (4.7)

9 (2.3)

 Other medical

23 (3.5)

80 (5.1)

25 (3.3)

16 (4.0)

 Non-operative trauma

104 (16.0)

153 (9.7)

64 (8.5)

23 (5.8)

 Postoperative

205 (31.6)

484 (30.8)

193 (25.7)

77 (19.4)

Admission category, N (%)

 Non-operative

444 (68.4)

1088 (69.2)

557 (74.3)

320 (80.6)

<0.0001

 Postoperative

205 (31.7)

484 (30.8)

193 (25.7)

77 (19.4)

Chronic co-morbidities, N (%)

 Chronic liver disease

60 (9.6)

196 (12.7)

93 (12.7)

37 (9.5)

0.08

 Advanced heart failure

87 (13.8)

324 (20.9)

177 (24.1)

145 (37.1)

<0.0001

 Chronic respiratory disease

84 (13.4)

231 (14.9)

120 (16.4)

55 (14.1)

0.44

 Chronic renal disease

41 (6.5)

234 (15.1)

140 (19.1)

95 (24.2)

<0.0001

 Chronic immunosuppression

64 (10.2)

195 (12.6)

67 (9.1)

31 (7.9)

0.01

 Diabetes, N (%)

178 (27.4)

618 (39.3)

289 (38.5)

208 (52.4)

<0.0001

 Chronic hypertension, N (%)

199 (30.7)

652 (41.5)

302 (40.3)

203 (51.1)

<0.0001

Mechanical ventilation, N (%)

477 (73.5)

1181 (75.1)

660 (88.0)

355 (89.4)

<0.0001

Vasopressor use, N (%)

213 (32.8)

677 (43.1)

445 (59.3)

266 (67.0)

<0.0001

Sepsis, N (%)

124 (19.1)

375 (23.9)

214 (28.5)

126 (31.7)

<0.0001

Admission post-cardiac arrest, N (%)

9 (1.4)

77 (4.9)

83 (11.1)

75 (18.9)

<0.0001

Admission physiologic characteristics

 Acute kidney injury, N (%)

51 (7.9)

232 (14.8)

182 (24.3)

107 (27)

<0.0001

 Heart rate >150 beat/minute, Mean ± SD

0.02 ± 0.14

0.05 ± 0.21

0.06 ± 0.25

0.09 ± 0.29

<0.0001

 Systolic Blood pressure <90 mmHg, Mean ± SD

0.20 ± 0.40

0.27 ± 0.45

0.39 ± 0.49

0.40 ± 0.49

<0.0001

 Urine output (ml 1st 24 hrs), Mean ± SD

2252.9 ± 1571.9

1877.6 ± 1415.7

1702.9 ± 1604.0

1422.4 ± 1301.3

<0.0001

 PaO2/FiO2 <200, N (%)

204 (40.8)

598 (43.4)

360 (54.1)

187 (54.4)

<0.0001

Lab findings, Mean ± SD

 Platelet, 109/L

257.3 ± 167.5

212.3 ± 142.7

186.9 ± 150.3

192.7 ± 136.4

<0.0001

 Bilirubin, μmol/l

37.8 ± 87.5

55.2 ± 119.8

67.1 ± 132.7

44.4 ± 82.1

0.0002

 Creatinine, μmol/l

108.4 ± 112.4

156 ± 149.3

192.2 ± 163.5

247.9 ± 198.3

<0.0001

 Lactate, mg/dL

2.30 ± 2.30

3.02 ± 2.93

4.73 ± 4.20

5.70 ± 5.05

<0.0001

 INR

1.35 ± 0.70

1.54 ± 0.87

1.79 ± 1.185

1.97 ± 1.35

<0.0001

  1. SD standard deviation
  2. aThe cardiovascular admission category includes admissions related to cardiovascular failure or insufficiency from hypertensive crisis, rhythm disturbances, acute decompensation of heart failure, hemorrhagic/hypovolemic shock, sepsis and dissecting thoracic/abdominal aneurysm. Please refer to the Supplement for a complete list of admission categories