From: Intrathecal morphine administration reduces postoperative pain and peripheral endocannabinoid levels in total knee arthroplasty patients: a randomized clinical trial
Placebo
Morphine
Number of Subjects
25
17
Gender (M/F)
6/19
8/9
Age
66.2 ± 1.8
64.0 ± 2.1
BMI (kg/m2)
32.2 ± 1.1
31.2 ± 1.3
History of Mood Disorders (Depression and/or Anxiety)
8
7
Preoperative Opioid Use
5
1