0.75% ropivacaine | 0.375% ropivacaine | 0.2% ropivacaine | |||||||
---|---|---|---|---|---|---|---|---|---|
< 60 yrs | > 60 yrs | P value | < 60 yrs | > 60 yrs | P value | < 60 yrs | > 60 yrs | P value | |
Age (yrs) | 50.3 ± 10.5 | 68.0 ± 6.1 | 45.5 ± 14.8 | 69.1 ± 5.0 | 50.1 ± 9.7 | 70.3 ± 4.9 | |||
MAP (mmHg) | 0.190 | 0.577 | 0.851 | ||||||
Load | 87.9 ± 13.2 | 94.1 ± 16.5 | 90.2 ± 14.8 | 90.1 ± 12.3 | 92.5 ± 17.9 | 94.7 ± 14.1 | |||
10 min | 76.1 ± 14.8 | 69.7 ± 18.9 | 71.2 ± 12.3 | 74.4 ± 15.9 | 75.8 ± 14.7 | 81.4 ± 16.0 | |||
20 min | 75.3 ± 16.7 | 65.7 ± 11.8 | 70.3 ± 15.5 | 72.7 ± 14.9 | 74.1 ± 15.3 | 82.7 ± 17.4 | |||
30 min | 76.0 ± 14.8 | 72.4 ± 16.3 | 81.0 ± 26.0 | 72.9 ± 14.3 | 73.8 ± 12.2 | 77.7 ± 15.9 | |||
CVP (mmHg) | 0.011 | 0.225 | 0.300 | ||||||
Load | 4.7 ± 2.7 | 4.8 ± 2.4 | 4.1 ± 1.9 | 4.5 ± 2.7 | 5.8 ± 2.7 | 3.9 ± 1.8 | |||
10 min | 4.7 ± 2.7 | 4.4 ± 2.9 | 3.4 ± 2.3 | 4.2 ± 3.1 | 5.3 ± 2.7 | 4.1 ± 2.3 | |||
20 min | 4.5 ± 2.9 | 3.9 ± 2.3 | 3.6 ± 2.0 | 4.6 ± 3.0 | 5.3 ± 2.4 | 5.1 ± 2.8 | |||
30 min | 5.0 ± 2.8 | 4.1 ± 2.2 | 4.1 ± 2.5 | 4.5 ± 3.0 | 5.5 ± 2.9 | 5.2 ± 2.6 | |||
SVV (%) | 0.032 | 0.522 | 0.885 | ||||||
Load | 7.5 ± 2.9 | 9.2 ± 3.0 | 10.6 ± 6.7 | 7.9 ± 3.6 | 8.2 ± 2.2 | 9.3 ± 3.7 | |||
10 min | 10.4 ± 5.8 | 13.8 ± 7.3 | 8.5 ± 2.0 | 9.8 ± 5.2 | 9.5 ± 3.6 | 9.5 ± 4.2 | |||
20 min | 8.9 ± 3.9 | 14.1 ± 7.6 | 7.7 ± 2.2 | 8.5 ± 2.8 | 7.6 ± 2.0 | 9.8 ± 5.0 | |||
30 min | 11.0 ± 6.2 | 12.3 ± 5.8 | 7.8 ± 2.7 | 10.2 ± 3.6 | 8.6 ± 2.3 | 8.5 ± 2.9 | |||
SVRI (dynes-sec/cm–5/m2) | 0.024 | 0.011 | 0.320 | ||||||
Load | 1847.7 ± 500.1 | 2300.0 ± 634.6 | 2098.3 ± 660.7 | 2536.0 ± 659.3 | 2124.8 ± 558.0 | 2604.2 ± 634.1 | |||
10 min | 1811.4 ± 453.0 | 2026.5 ± 553.4 | 1898.6 ± 696.8 | 2189.9 ± 512.9 | 1828.0 ± 458.9 | 2456.8 ± 703.5 | |||
20 min | 1978.6 ± 374.4 | 1941.4 ± 344.0 | 1977.8 ± 747.1 | 2173.1 ± 282.9 | 1809.1 ± 407.1 | 2392.5 ± 469.1 | |||
30 min | 1967.1 ± 414.2 | 2140.2 ± 525.1 | 1945.0 ± 674.9 | 2185.6 ± 360.2 | 1888.4 ± 497.2 | 2342.4 ± 512.6 | |||
SVI (mL/beat/m2) | 0.011 | 0.002 | 0.342 | ||||||
Load | 39.6 ± 9.0 | 35.2 ± 10.0 | 38.9 ± 11.4 | 33.5 ± 6.5 | 37.7 ± 8.7 | 34.4 ± 7.2 | |||
10 min | 38.4 ± 7.6 | 34.7 ± 6.9 | 39.3 ± 13.9 | 35.1 ± 7.2 | 41.7 ± 11.1 | 36.5 ± 9.0 | |||
20 min | 38.6 ± 8.9 | 34.1 ± 8.2 | 37.4 ± 11.2 | 34.6 ± 7.8 | 42.8 ± 11.7 | 38.8 ± 13.7 | |||
30 min | 37.7 ± 9.6 | 33.8 ± 8.8 | 40.8 ± 10.8 | 35.2 ± 6.0 | 41.8 ± 10.4 | 37.5 ± 5.9 | |||
CI (L/min/m2) | 0.901 | 0.082 | 0.512 | ||||||
Load | 3.8 ± 0.9 | 3.2 ± 0.9 | 3.5 ± 1.1 | 2.8 ± 0.6 | 3.4 ± 0.8 | 2.9 ± 0.9 | |||
10 min | 3.3 ± 0.8 | 2.6 ± 0.6 | 3.1 ± 0.8 | 2.6 ± 0.5 | 3.2 ± 0.8 | 2.6 ± 0.6 | |||
20 min | 2.9 ± 0.6 | 2.5 ± 0.4 | 3.0 ± 1.0 | 2.5 ± 0.5 | 3.2 ± 1.0 | 2.6 ± 0.5 | |||
30 min | 2.9 ± 0.7 | 2.6 ± 0.5 | 3.3 ± 1.1 | 2.5 ± 0.4 | 3.1 ± 1.0 | 2.5 ± 0.6 | |||
HR (beats/min) | 0.025 | 0.776 | 0.119 | ||||||
Load | 93.0 ± 13.0 | 87.3 ± 15.3 | 86.9 ± 12.6 | 81.6 ± 18.1 | 85.0 ± 13.2 | 85.5 ± 19.7 | |||
10 min | 83.5 ± 14.9 | 79.4 ± 17.0 | 74.0 ± 12.0 | 77.9 ± 16.9 | 76.9 ± 13.3 | 77.7 ± 22.4 | |||
20 min | 80.3 ± 18.1 | 78.2 ± 13.4 | 75.1 ± 16.1 | 77.8 ± 17.0 | 72.8 ± 11.5 | 72.7 ± 15.1 | |||
30 min | 80.1 ± 17.1 | 80.1 ± 16.6 | 77.5 ± 11.2 | 72.8 ± 13.0 | 74.5 ± 16.3 | 70.8 ± 16.2 | |||
Total-ephedrine (mg) | 10.0 ± 13.5 | 9.0 ± 14.4 | 0.833 | 0.4 ± 1.4 | 2.6 ± 6.1 | 0.238 | 0.5 ± 2.2 | 0.0 ± 0.0 | 0.337 |