From: Patients with glycogen storage diseases undergoing anesthesia: a case series
 | Clinical presentation | |
---|---|---|
Pt | Neurologic/Muscular | Other |
GSD type 0 | ||
 1 | Muscle weakness | OSA; hypertrophic cardiomyopathy; hypertension |
GSD type I (von Gierke) | ||
 2 | Muscle weakness; gait abnormalities | Lactic acidosis; hypoglycemia; hepatic adenoma |
 3 | None reported | Hypoglycemia |
 4 | None reported | Hypertension; hypoglycemia; lactic acidosis |
 5 | Seizures | Hyperuricemia; lactic acidosis; hypoglycemia |
 6 | Developmental delay; velopharyngeal insufficiency | Hypoglycemia |
 7 | Fatigue, muscle weakness | Hypoglycemia |
GSD type II (Pompe) | ||
 8 | Severe scoliosis; muscle weakness; wheelchair-bound | Respiratory failure (BiPAP); restricted lung disease |
 9 | Muscle weakness; hypotonia | None reported |
 10 | Muscle weakness | Respiratory failure (BiPAP); pulmonary hypertension; CHF; dilated cardiomyopathy; atrial fibrillation |
 11 | Muscle weakness | None reported |
 12 | Muscle weakness | CHF; dilated cardiomyopathy |
 13 | Muscle weakness | Respiratory failure (BiPAP) |
 14 | Muscle weakness | Dyspnea; hypertension |
 15 | None reported | Hypertrophic cardiomyopathy; ventricular tachycardia |
GSD type IV (Andersen) | ||
 16 | Developmental delay | Hepatosplenomegaly |
GSD type V (McArdle) | ||
 17 | Muscle weakness; cervical radiculopathy | None reported |
 18 | Muscle stiffness; increased serum creatine kinase | None reported |
 19 | Muscle weakness | None reported |
 20 | Muscle weakness | None reported |
 21 | Muscle cramps; exercise intolerance | None reported |
 22 | Exercise intolerance | None reported |
 23 | Muscle weakness | None reported |
 24 | Muscle weakness and stiffness | None reported |
 25 | Muscle weakness | None reported |
 26 | Episodes of rhabdomyolysis; exercise intolerance | None reported |
 27 | Muscle weakness | Hypertension |
GSD type VI (Hers) | ||
 28 | None reported | Lactic acidosis |
GSD type VII (Tarui) | ||
 29 | Muscle weakness | None reported |
Unidentified, likely glycolytic defect | ||
 30 | Proximal muscle myopathy | Hypoglycemia |