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Table 2 Resuscitation Outcomes for LiEL, LiE and LiL groups

From: Levosimendan combined with epinephrine improves rescue outcomes in a rat model of lipid-based resuscitation from bupivacaine-induced cardiac arrest

Characteristics Group LiEL
(n = 18)
Group LiE
(n = 18)
Group LiL
(n = 18)
Rate of ROSC,% 100%# 94.4%# 50%
Survival rate,% 100% 61.1%* 50%*
Time to first heart beat (s) 44 ± 12 137 ± 85* 170 ± 90*
Time to ROSC (s) 142(120,151) 317(238,495)* 1590(313,2400)*
Epinephrine cumulative dose (μg/kg) 3 (2, 3) 6 (4, 8)* _____________
  1. Data are given as mean ± SD or medians and interquartile. The rate of ROSC in each group displayed differences (P < 0.001; LiEL vs LiL, P = 0.001; LiE vs LiL, P = 0.007). The LiEL, LiE, LiL groups displayed differences in survival (P = 0.003; LiEL vs LiE, P = 0.008; LiEL vs LiL, P = 0.001). The LiEL, LiE, and LiL groups displayed differences in time to first heart beat and ROSC (first heart beat: P < 0.001; LiE vs LiEL, P = 0.001; LiL vs LiEL, P < 0.001. ROSC: P < 0.001; LiEL vs LiE, P < 0.001; LiEL vs LiL, P < 0.001). The LiEL and LiE groups displayed differences in epinephrine cumulative dose (P < 0.001). # P < 0.01 vs LiL, * P < 0.01 vs LiEL. ROSC indicates return of spontaneous circulation