Skip to main content

Table 2 Resuscitation Outcomes for LiEL, LiE and LiL groups

From: Levosimendan combined with epinephrine improves rescue outcomes in a rat model of lipid-based resuscitation from bupivacaine-induced cardiac arrest

Characteristics

Group LiEL

(n = 18)

Group LiE

(n = 18)

Group LiL

(n = 18)

Rate of ROSC,%

100%#

94.4%#

50%

Survival rate,%

100%

61.1%*

50%*

Time to first heart beat (s)

44 ± 12

137 ± 85*

170 ± 90*

Time to ROSC (s)

142(120,151)

317(238,495)*

1590(313,2400)*

Epinephrine cumulative dose (μg/kg)

3 (2, 3)

6 (4, 8)*

_____________

  1. Data are given as mean ± SD or medians and interquartile. The rate of ROSC in each group displayed differences (P < 0.001; LiEL vs LiL, P = 0.001; LiE vs LiL, P = 0.007). The LiEL, LiE, LiL groups displayed differences in survival (P = 0.003; LiEL vs LiE, P = 0.008; LiEL vs LiL, P = 0.001). The LiEL, LiE, and LiL groups displayed differences in time to first heart beat and ROSC (first heart beat: P < 0.001; LiE vs LiEL, P = 0.001; LiL vs LiEL, P < 0.001. ROSC: P < 0.001; LiEL vs LiE, P < 0.001; LiEL vs LiL, P < 0.001). The LiEL and LiE groups displayed differences in epinephrine cumulative dose (P < 0.001). # P < 0.01 vs LiL, * P < 0.01 vs LiEL. ROSC indicates return of spontaneous circulation