Table 8 Rescue medication against constipation
Tapentadol | Oxycodone/ Naloxone | |||||
|---|---|---|---|---|---|---|
N | Mean dose | N | Mean dose | p-value (Chi2) | p-value (t-test) | |
PEG3350 (g) | ||||||
Day 1 | 0 | 0 | 1 | 7 | ||
Day 2 | 6 | 28 | 3 | 24 | ||
Day 3 | 12 | 27 | 10 | 22 | ||
Day 4 | 12 | 28 | 8 | 25 | ||
Day 5 | 10 | 32 | 9 | 24 | ||
Total over 5 days | 17 | 68 | 13 | 55 | 0.44 | 0.47 |
Sodium picosulfate (mg) | ||||||
Day 1 | 0 | 0 | 0 | 0 | ||
Day 2 | 1 | 10 | 0 | 0 | ||
Day 3 | 3 | 10 | 3 | 6 | ||
Day 4 | 6 | 9 | 2 | 10 | ||
Day 5 | 2 | 8 | 0 | 0 | ||
Total over 5 days | 10 | 11 | 5 | 7 | 0.18 | 0.07 |
Bisacodyl (mg) | ||||||
Day 1 | 1 | 5 | 0 | 0 | ||
Day 2 | 0 | 0 | 0 | 0 | ||
Day 3 | 0 | 0 | 0 | 0 | ||
Day 4 | 2 | 10 | 1 | 5 | ||
Day 5 | 1 | 20 | 0 | 0 | ||
Total over 5 days | 4 | 11 | 1 | 5 | 0.18 | 0.44 |
Lactulose (g) | ||||||
Day 1 | 0 | 0 | 0 | 0 | ||
Day 2 | 0 | 0 | 1 | 7 | ||
Day 3 | 0 | 0 | 1 | 7 | ||
Day 4 | 2 | 10 | 1 | 7 | ||
Day 5 | 2 | 13 | 1 | 7 | ||
Total over 5 days | 3 | 16 | 4 | 7 | 0.70 | 0.13 |