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Table 3 Cumulative study medication during the 5-days observation period for the different types of procedures

From: Combatting pain after orthopedic/trauma surgery- perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone

Operation

Cumulative study medication (mg)

Tapentadol

(mean ± std)

Oxycodone/naloxone

(mean ± std)

Open reduction and internal fixation, ORIF

449 ± 228

94 ± 48

Closed reposition and intramedullary nailing

540 ± 238

82 ± 34

Joint replacement

567 ± 303

81 ± 43

Reconstruction of ligaments and muscle

580 ± 199

104 ± 64

Fixateur externe

700

.