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Table 7 Results of myocardial infarction

From: General vs. neuraxial anaesthesia in hip fracture patients: a systematic review and meta-analysis

Author/Reference

Study type

Anaesthesia

Sample size

Outcome parameter

Results

Conclusion

Basques et al. 2015 [8]

Retrospective observational study

GA vs. SA

n = 9.842

GA = 7.253 (73.7%)

SA = 2.589 (26.3%)

Myocardial infarction

SA vs. GA: 1.9% vs. 1.9%; OR 1.00, 95% CI 0.71 to 1.39, p = 0.510

The incidence of myocardial infarction was similar in the two groups.

Biboulet et al. 2012 [32]

Randomised controlled study

GA vs. SA (propofol, sevoflurane)

n = 45

GA = 30

SA = 15

Myocardial infarction

SA vs. GA: 0 vs. 1, p = 1.0

The incidence of myocardial infarction was similar between the two groups.

Chu et al. 2015 [25]

Retrospective observational study

GA vs. NA (spinal/epidural)

n = 104.088

GA = 52.044

NA = 52.044

Myocardial infarction

NA vs. GA: 169 (0.32%) vs. 188 (0.36%), p = 0.31

The incidence of myocardial infarction was similar between the two groups.

Fields et al. 2010 [9]

Retrospective observational study

GA vs. SA

n = 6.133 GA = 4.318 (72.6%) SA = 1.815 (27.4%)

Myocardial infarction

SA vs. NA: 1.71% vs. 1.75%, p = 0.92

The incidence of myocardial infarction was similar between the two groups.

Heidari et al. 2011 [33]

Randomised controlled study

GA vs. NA (EA/SA)

n = 270

GA = 197

NA = 190

Myocardial infarction

NA vs. GA: 1 (0.6%) vs. 1 (0.5%),

The incidence of myocardial infarction was similar between the two groups.

Neuman et al. 2012 [27]

Retrospective observational study

GA vs. NA

n = 18.158

GA = 12.904

NA = 5.254

Myocardial infarction

NA vs. GA: 97 (1.9%) vs. 266 (2.1%), p = 0.348

The incidence of myocardial infarction was similar between the two groups.

Parker et al. 2015 [31]

Randomised controlled study

GA vs. SA

n = 322 GA = 164 (50.93%) SA = 158 (49.07%)

Myocardial infarction

SA vs. GA: 1 (0.6%) vs. 1 (0.6%), p = 1.0

The incidence of myocardial infarction was similar between the two groups.

Seitz et al. 2014 [19]

Retrospective observational study

GA (inhalational, intravenous, GA combined with epidural or local anaesthesia) vs. SA

n = 20.973 GA = 8.818 (42.1%) SA = 12.155 (57.9%)

Myocardial infarction

SA vs. GA: 454 (7.4%) vs. 501 (8.2%), p = 0.07

The incidence of myocardial infarction was similar between the two groups.

Tung et al. 2016 [24]

Retrospective observational study

GA vs. RA (epidural/spinal)

n = 17.189 GA = 6.063 (35.1%) NA = 11.153 (64.9%)

Myocardial infarction

NA vs. GA: 10 (0.1%) vs. 10 (0.1%), p = 0.162

The incidence of myocardial infarction was similar between the two groups.

Whiting et al. 2015 [22]

Retrospective observational study

GA vs. SA

n = 7.764 GA = 5.840 SA = 1.813

Myocardial infarction

SA vs. GA: Odds ratio 0.84; 95% CI 0.50-1.43, p = 0.532

The incidence of myocardial infarction was similar between the two groups.

  1. CI confidence interval, GA general anaesthesia, NA neuraxial anaesthesia, OR odds ratio, SA spinal anaesthesia, RA regional anaesthesia