Table 4 Results of the 30-day mortality

Basques et al. 2015 [8]

Retrospective observational study

GA vs. SA

n = 9.842 GA = 7.253 (73.7%) SA = 2.589 (26.3%)

30-day mortality

GA vs. SA: 6.2% vs. 6.4%; (OR 0.98, 95% CI 0.82 to 1.20, p = 0.908)

There was no difference related to the mortality.

Biboulet et al. 2012 [32]

Randomised controlled study

SA vs. GA (propofol, sevoflurane)

n = 45

GA = 30 SA = 15

30-day mortality

SA vs.GA: 1 (6.7%) vs. 1(7.1%), p = 0.76

There was no difference related to the mortality

Brox et al. 2016 [23]

Retrospective observational study

GA vs. SA

n = 7.585 GA = 4.257 (56%) SA = 3.059 (40%) Mixed = 269 (4%)

30-day mortality

30-day mortality: GA = 177 (4%) vs. SA = 113 (4%)

There was no difference related to the mortality.

Fields et al. 2010 [9]

Retrospective observational study

GA vs. SA

n = 6.133 GA = 4.318 (72.6%) SA = 1.815 (27.4%)

30-day mortality

SA vs. GA: 30-day mortality: 6.67% vs. 5.84%, p = 0.21

There was no difference related to the mortality.

Heidari et al. 2011 [33]

Randomised controlled study

GA vs. NA (Epidural/spinal)

n = 387 GA = 197 NA = 190

30-day mortality

GA vs. SA: 0 vs. 2, p = 0.299

There was no differencerelated to the mortality.

Helwani et al. 2015 [10]

Retrospective observational study

GA vs. NA(SA/EA)

n = 12.929 GA = 7.826 (60.5%) RA = 5.103 (39.5%) [SA = 4.377 (85.8%); EA = 126 (2.5%)]

30-day mortality

NA vs. GA: OR 0.78, 95% CI 0.43 to 1.42; p > 0,05

There was no difference in the mortality.

Kim et al. 2013 [13]

Retrospective observational study

GA vs. SA vs. EA

n = 506 GA = 246 (48.62%) SA = 249 (49.21%) EA = 11 (2.17%)

30-day mortality

GA = 7 (2.8%); SA = 4 (1.6%); EA = 0 (0.0%); p = 0.57

There was no difference in the mortality.

Neuman et al. 2014 [15]

Retrospective observational study

GA vs. NA (spinal/epidural)

n = 56.729 GA = 40.825 (72%) RA = 15.904 (28%)

30-day mortality

RA = 5.3%, GA = 5.4% (difference 0.1%; 95% CI 0.5 to 0.3; p = 0.55)

30-day mortality did not differ significantly between GA and NA.

Parker et al. 2015 [31]

Randomised controlled study

GA vs. SA

n = 322 GA = 164 (50.93%) SA = 158 (49.07%)

30-day mortality

30-day mortality: GA vs SA: 8 (4.9%) vs. 5 (3.2%); p = 0.57

There was no difference in the mortality.

Seitz et al. 2014 [19]

Retrospective observational study

GA (inhalational, intravenous, GA combined with epidural or local anaesthesia) vs. SA

n = 20.973 GA = 8.818 (42.1%) SA = 12.155 (57.9%)

30-day mortality

GA vs. SA: 30-day mortality: GA = 691 (11.3%) vs. SA = 665 (10.8%), p = 0.44

There was no difference in the mortality.

Sevtap et al. 2012 [20]

Retrospective observational study

GA vs. SA vs. EA

n = 185 GA = 67 (36.21%) SA = 67 (36.21%) EA = 51 (27.58%)

30-day-mortality

30-day mortality: GA = 4 (1.4%), SA = 6 (5.9%), EA = 4 (5.8%), p = 0.805

There was no difference in the mortality.

Tung et al. 2016 [24]

Retrospective observational study

GA vs. NA

n = 17.189 GA = 6.063 (35.1%) RA = 11.153 (64.9%)

30-day mortality

30-day mortality: GA = 104 (1.7%), NA = 189 (1.7%), p = 0.891, (OR 0.89, 95% CI 0.67 to 1.18, p = 0.409)

There was no difference in the mortality.

White et al. 2014 [21]

Retrospective observational study

GA vs. SA

n = 65.535 GA = 35.373 (53.97%) SA = 23.665 (36.11%)

30-day mortality

30-day mortality: GA = 1.066 (7.0%) vs. SA = 1.345 (7.3%); p = 0.053

No notable differences between GA and SA.

White et al. 2016 [26]

Retrospective observational study

GA vs. SA (with or without peripheral nerve block)

n = 11.085

GA = 985

GA with block = 4.364

GA + SA = 458

SA = 1.506

SA with block = 3.234

Unknown = 538

30-day mortality

30-day mortality:

GA vs. SA: 291 (5.4%) vs. 224 (4.7%)

No notable differences between GA and SA.