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Table 2 Comparison of characteristics two-by-two, by the presence or absence of pulmonary complication(s)

From: Risk factors for pulmonary complications after hepatic resection: role of intraoperative hemodynamic instability and hepatic ischemia

Variable and Level(s)

No PPC (n = 62)

PPC (n = 32)

p

Mean ± SD or n(%)

Mean ± SD or n(%)

General characteristics

 Age

60.9 ± 13.9

60.2 ± 12.9

0.81

 Male gender

32 (52)

24 (75)

0.03

 Body Mass Index

24.0 ± 4.3

26.3 ± 5.9

0.04

 ASA score

  

0.42

  1

3 (5)

1 (3)

 

  2

29 (47)

11 (34)

 

  3

30 (48)

20 (62)

 

 Daily tobacco consumption

17 (27)

13 (41)

0,20

 Daily alcohol consumption

4 (6)

9 (28)

0,007

General comorbidities

 COPD

4 (6)

5 (16)

0,16

 Asthma

3 (5)

1 (3)

0,70

 ASS

3 (5)

3 (9)

0,40

 Cardiomyopathy

3 (5)

7 (22)

0,02

 Chronical kidney failure

7 (11)

1 (3)

0,21

 Diabetes

5 (8)

6 (19)

0,14

Hepatic comorbidities

 Non cancer hepatopathy

11 (18)

13 (41)

0,02

 Cirrhosis

9 (14)

10 (31)

0,06

 Portal hypertension

4 (6)

4 (12)

0,33

 NASH

6 (6)

6 (6)

0,33

 Cholestasis

3 (5)

3 (9)

0,40

 Liver underwent chemiotherapy

3 (5)

1 (3)

0,70

Pre-surgery biological workup

 Hemoglobin level in g/dL

12.9 ± 1.7

13.2 ± 1.9

0.44

 Platelets level in G/L

227 ± 97

215 ± 68

0.55

 White blood cells level in G/L

7.3 ± 6.1

7.1 ± 2.2

0.83

 Prothrombin ratio

99.1 ± 12.4

98.1 ± 14.1

0.74

 Fibrinogen level in g/L

4.1 ± 1.3

4.4 ± 1.4

0.35

 Creatinin level in μmol/mL

86.2 ± 52.3

76.6 ± 19.6

0.36

 Abnormal GGT

21 (36)

22 (71)

0,002

 Abnormal AST

21 (36)

17 (57)

0,07

 Abnormal ALT

15 (26)

16 (53)

0,01

 Abnormal total Bilirubin

10 (17)

3 (11)

0,51

 Abnormal APL

10 (21)

14 (48)

0,01

 Etiology of surgery

  

0.17

  Primituve HCC

11 (18)

11 (34)

 

  Metastasis

38 (61)

17 (53)

 

 Others

13 (21)

4 (12)

 

Surgery charactetistics

 Major hepatectomy

23 (37)

22 (69)

0.005

 Presence of clamping

41 (66)

28 (87)

0.10

 Clamping by PTC

36 (58)

22 (69)

0,31

 Clamping by TVEL

6 (10)

9 (28)

0,03

 Ischemia duration in mn

22.5 ± 20.5

34.3 ± 21.2

0.01

 Bleeding volume in mL

510.0 ± 417.3

562.9 ± 335.7

0.54

 Duration of surgery in mn

246.2 ± 92.3

269.9 ± 80.0

0.22

Anaesthetic characteristics

 Blood transfusion

17 (27)

10 (31)

0,70

 Diuresis volume

418.4 ± 337.4

362.8 ± 251.9

0.41

 Use of vasopressive drug(s)

25 (40)

22 (69)

0,01

  1. PPC postoperative pulmonary complication, ASA score American Society of Anesthesiology score, COPD chronic obstructive pulmonary disease, SD standard deviation, ASS apnoea sleep syndrome, NASH non alcoholic steatohepatitis, HCC hepatocellular carcinoma, TVEL Total vascular exclusion of the liver, PTC portal triad clamping, ARDS acute respiratory distress syndrome, ASS apnoea sleep syndrome, PO pulmonary oedema, HCV hepatitis C virus, HBV hepatitis B virus, GGT gamma-glutamyltransferase, AST aspartate aminotransferase, ALT alanine aminotransferase, total bilirubin, APL alkaline phosphatase