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Table 1 Association of clinical characteristics and 7-day mortality in the cohort

From: A clinical score to predict mortality in septic acute kidney injury patients requiring continuous renal replacement therapy: the HELENICC score

 

Non Survivors

Survivors

p value

(n = 84)

(n = 102)

Age (years), mean ± SD

67 ± 16

70 ± 13

0.14

Male sex, n (%)

42 (50%)

62 (61%)

0.14

Medical condition, n (%)

57 (68%)

50 (49%)

0.01

Primary site of infection, n (%)

 Pulmonary

49 (58%)

55 (54%)

0.55

 Urinary

6 (7.1%)

9 (8.8%)

0.68

 Abdominal

8 (9.5%)

12 (12%)

0.62

 BSI a

14 (17%)

15 (15%)

0.71

 CRBSI b

5 (6.0%)

11 (1%)

0.24

 SSTIs c

2 (2.4%)

0

0.20

Comorbidities, n (%)

 Heart failure

28 (33%)

50 (49%)

0.03

 Coronary artery disease

25 (30%)

42 (41%)

0.11

 Pulmonary disease

8 (9.5%)

10 (9.8%)

1.0

 Liver failure

55 (66%)

32 (31%)

<0.001

 Cerebral vascular disease

7 (8.3%)

8 (7.8%)

0.90

 Diabetes

23 (27%)

37 (36%)

0.20

Norepinephrine use

78 (93%)

80 (78%)

0.006

Admission creatinine (mg/dl), median (IQR)

1.0 (0.8–1.6)

1.2 (0.9–2.2)

0.14

Laboratory values before RRT d, median (IQR)

 Urea (mg/dl)

142 (86–198)

137 (78–206)

0,57

 Chloride (mmol/l)

109 (104–112)

107 (104–110)

0,41

 Creatinine (mg/dl)

2.2 (1.5–3.3)

2.7 (2.0–3.8)

0.005

 Potassium (mmol/l)

4.7 (3.8–5.4)

4.3 (3.8–5.0)

0.05

 Sodium (mmol/l)

133 (127–137)

135 (132–139)

0.009

 Lactate (mmol/l)

3.0 (1.8–5.1)

1.8 (1.4–2.7)

<0.001

 Hemoglobin (g/dl)

8.9 (8.0–9.9)

9.1 (8.2–10)

0.21

 White cell count (103 mm3/l)

17 (6.6–24)

16 (11–22)

0.64

 Platelets count (103 mm3/l)

94 (48–176)

155 (79–265)

0.001

 24 h urinary output (ml/kg/h)

320 (150–600)

300 (100–600)

0.57

 Fluid Balance (ml)

7782 (4175–11,389)

6891 (4090–9692)

0.007

  1. a BSI bloodstream infections
  2. b CRBSI cateter-related bloodstream infections
  3. c SSTIs skin and soft tissue infections
  4. d RRT renal replacement therapy