Supplement of levosimendan to epinephrine improves initial resuscitation outcomes from asphyxial cardiac arrest

BMC Anesthesiology

Table 2 Resuscitation Outcomes for EL, E and L Groups

	EL group (n = 10)	E group (n = 10)	L group (n = 10)	P value
Rate of ROSC, n (%)	10 (100%)^##	8 (80%)	2 (20%)^*	<0.001
Survival rate, n (%)	10 (100%)^*##	4 (40%)	2 (20%)	0.001
Time to CA, s	167 ± 28	167 ± 26	165 ± 19	0.986
Time to return of pulse, s	39 ± 7^##	44 ± 10	99 ± 19^**	< 0.001
Time to ROSC, s	47 ± 7^**#	81 ± 22	277 ± 10^**	0.001

Normal distributed data are given as mean ± SD. The EL, E and L groups displayed differences in the rate of ROSC (P < 0.001; EL vs. E, P =0.474; EL vs. L, P = 0.001; E vs. L, P =0.023). The EL, E and L groups displayed difference in rates of survival (P = 0.001; EL vs. E, P = 0.011; EL vs. L, P = 0.001; E vs. L, P =0.628). There were no differences among the three groups in the time to CA (P > 0.05). The EL, E and L groups displayed differences in the time to return of pulse (P < 0.001; EL vs. E, P =0.354; EL vs. L, P < 0.001; E vs. L, P < 0.001). The EL, E, and L groups displayed differences in the time to ROSC (P = 0.001; EL vs. E, P = 0.008; EL vs. L, P = 0.021; E vs. L, P < 0.001), ^* P < 0.05, ^** P < 0.01, versus group E;^# P < 0.05, ^## P < 0.01, versus group L. ROSC indicates return of spontaneous circulation. CA indicates cardiac arrest

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