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Fig. 9 | BMC Anesthesiology

Fig. 9

From: Sevoflurane and isoflurane inhibit KCl-induced Class II phosphoinositide 3-kinase α subunit mediated vasoconstriction in rat aorta

Fig. 9

Effects of sevoflurane and isoflurane on KCl-induced CPI-17 phosphorylation in rat aortic smooth muscle. The aortas strips were incubated in the presence of 1.7 %, 3.4 % sevoflurane (SEVO) or 1.2 %, 2.3 % isoflurane (ISO), or 1 mM LY294002, or 1 uM Y27632 for 15 min before and during exposure to KCl. CPI-17 phosphorylation development in response to anesthetic or inhibitor was expressed as percentage relative to that induced by KCl. * P < 0.05 versus the value in the presence of KCl, # P < 0.05 versus the baseline without KCl (n = 7, each)

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BMC Anesthesiology

ISSN: 1471-2253

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