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Fig. 6 | BMC Anesthesiology

Fig. 6

From: Sevoflurane and isoflurane inhibit KCl-induced Class II phosphoinositide 3-kinase α subunit mediated vasoconstriction in rat aorta

Fig. 6

Effects of sevoflurane and isoflurane on member translocation of Rho kinase (Rock II) in response to KCl. The aortic strips were incubated in the presence of 0, 1.2 %, 2.3 % isoflurane (ISO,A), or 0, 1.7 %, 3.4 % sevoflurane (SEVO,B), or 1 mM LY294002, or 1 uM Y27632 for 15 min before and during exposure to KCl. The amount of Rock-II on the membrane was expressed as a percentage of the total value (i.e., membrane fraction plus cytosolic fraction). * P < 0.05, ** P < 0.01 versus the value in the presence of KCl, # P < 0.05 compared with the baseline without KCl (n = 7, each)

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BMC Anesthesiology

ISSN: 1471-2253

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