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Table 4 Cox regression analyses of septic patients with genetic variants in the Hypoxia-inducible factor-1α

From: Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis: a prospective observational trial

 

HR (95 %-CI)

p-value

rs11549465, CT vs. CC

1.42 (0.68–2.96)

0.350

rs11549465, TT vs. CC

NAa

NAa

Age, per year

1.023 (1.001–1.045)

0.040

Gender, male vs. female

1.70 (0.87–3.30)

0.120

Dialysis, yes vs. no

2.56 (1.15–5.67)

0.021

SAPS II, per point

1.02 (1.00–1.04)

0.059

  1. Analysis set N = 121. Missing data: rs11549465 genotype (n = 3), dialysis (n = 1), SAPS II (n = 3)
  2. aOnly n = 1 in the TT group, this patient was censored, thus no HR could be estimated