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Table 4 Sensitivity, specificity, positive predictive value and negative predictive value using 10 % difference in cardiac output between supine position to head-up tilt to define central hypovolemia

From: Can a central blood volume deficit be detected by systolic pressure variation during spontaneous breathing?

 

AUC

Optimal cut-off (%)

Sensitivity (%)

Specificity (%)

Positive predictive value (%)

Negative predictive value (%)

Stroke volume variation

      
 

No resistor

0.73 (0.46;1.00)

13

60

100

100

43

 

Expiratory resistor

0.82 (0.58;1.00)

28

70

100

100

50

 

Inspiratory resistor

0.75 (0.46;1.00)

18

50

100

100

38

 

Ins-/expiratory resistor

0.58 (0.28;0.88)

31

40

100

100

33

Systolic pressure variation

      
 

No resistor

0.43 (0.10;0.77)

19

20

100

100

27

 

Expiratory resistor

0.70 (0.37;1.00)

33

70

67

88

40

 

Inspiratory resistor

0.67 (0.25;1.00)

36

80

67

89

50

 

Ins-/expiratory resistor

0.96 (0.86;1.00)

37

78

100

100

60

Pulse pressure variation

      
 

No resistor

0.83 (0.61;1.00)

7

80

100

100

60

 

Expiratory resistor

0.73 (0.40;1.00)

4

70

67

88

40

 

Inspiratory resistor

0.73 (0.42;1.00)

7

50

100

100

38

 

Ins-expiratory resistor

0.59 (0.25;0.93)

12

67

67

86

40

Central venous oxygen saturation

     
 

No resistor

0.67 (0.29;1.00)

71

50

100

100

40

 

Expiratory resistor

0.46 (0.02;0.90)

70

50

50

75

25

 

Inspiratory resistor

0.42 (0.00;0.88)

77

50

50

75

25

 

Ins-expiratory resistor

0.50 (0.08;0.92)

77

33

100

100

33

  1. AUC area under the curve with confidence interval