Table 2 Haemodynamic variables and fluids administered during surgery
Ramosetron (n = 51) | Placebo (n = 52) | P value | |
|---|---|---|---|
Before anaesthesia induction | |||
Baseline heart rate (beats/min) | 66.1 ± 10.6 | 68.3 ± 11.7 | 0.317 |
Baseline mean arterial pressure (mmHg) | 96.3 ± 15.8 | 101.1 ± 14.6 | 0.117 |
During anaesthesia induction | |||
Use of ephedrine | 37 (72.5 %) | 31 (60.8 %) | 0.294 |
Use of phenylephrine | 8 (15.7 %) | 10 (19.6 %) | 0.796 |
At the end of surgery | |||
Use of vasopressors | 1 (1.9 %) | 1 (2.0 %) | 1.000 |
Use of inotropes | 1 (1.9 %) | 1 (2.0 %) | 1.000 |
Number of grafts (n) | 3.6 ± 0.7 | 3.3 ± 1.1 | 0.120 |
Total infused fluids (ml) | 3671.2 ± 1368.4 | 3557.1 ± 1308.9 | 0.666 |
Total infused crystalloids (ml) | 3083.3 ± 1699.3 | 2992.5 ± 1612.8 | 0.781 |
Total infused colloids (ml) | 585.9 ± 638.7 | 526.2 ± 814.6 | 0.680 |