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Fig. 4 | BMC Anesthesiology

Fig. 4

From: shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury

Fig. 4

Effects of siSCN9A on the burn -induced increase in Nav1.7 expression in the ipsilateral DRGs on day 7 after burn injury. a The amount of Nav1.7 reduced in DRG after burn injury while the GFP remained the same after administration to knockdown SCN9A gene. b the increased c-fos positive neurons have been reduced slightly after the SCN9A was knocked down; c and the up-regulated expression of Nav 1.7 was attenuated in injured DRGs after SCN9A was knocked down. (*p < 0.05, **p < 0.01, ***P < 0.001, NS: not statistically significant; versus the LV-NC-GFP group; n = 3/group)

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