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Table 3 Respiratory variables

From: Effects of the open lung concept following ARDSnet ventilation in patients with early ARDS

 

ARDSnet + OLC (n = 9)

ARDSnet-48 h (n = 6)

Baseline

ARDSnet-24 h

ARDSnet + OLC

Baseline

ARDSnet-24 h

ARDSnet-48 h

Pplat (cmH2O)

27 (23 – 27)

22 (20 – 26)

30 (24–31)

18 (15 – 25)

18 (15 – 23)

20 (17–24)

PEEP (cmH2O)

5 (5 – 5)

8 (8 – 11)

17 a b (17–19)

5 (5 – 5)

10 (5 – 11)

10 (7–11)

Driving Pressure (cmH2O)

14 (12 – 19)

12 (10 – 18)

12 (5–13)

13 (9 – 18)

10 (7 – 14)

11 (9.25 - 14)

VT (mL/kg)

10 (10 – 10)

8a (7 – 8)

7a (6–8)

10 (10 – 10)

7a (6 – 8)

7a (6–8)

VE (L/min)

9 (8 – 11)

8 (8 – 10)

7 (6–9)

9 (8 – 11)

7 (6 – 8)

7 (6–8)

Crs (mL/cmH2O)

32 (25 – 37)

42 (23 – 48)

46a (32–91)

43 (33 – 52)

48 (33 – 68)

40 (34–53)

PaO2/FIO2 (mmHg)

220 (175 – 238)

195 (184 – 246)

270a b, c (220–363)

233 (139 – 278)

162 (132 – 282)

177 (100–283)

SaO2

100 (96 – 100)

98 (96 – 98)

99 (98 – 99)

100 (99 – 100)

98a (94 – 99)

99a (97 – 100)

PaCO2 (mmHg)

41 (28 – 44)

44a (41 – 51)

49a (42–58)

37 (34 – 39)

47a (40 – 55)

43 (39–55)

pH

7.4 (7.3 – 7.4)

7.3 (7.3 – 7.4)

7.3 (7.3 - 7.4)

7.3 (7.3 – 7.5)

7.3 (7.2 – 7.4)

7.4 (7.2 - 7.4)

  1. Pplat plateau pressure of the respiratory system, Driving Pressure inspiratory pressure above PEEP in Pressure Controlled Ventilation Mode
  2. V T tidal volume in mL/kg of predicted body weight, VE minute ventilation, PEEP positive end-expiratory pressure, PaO 2 /FIO 2 arterial pressure of oxygen/inspiratory fraction of oxygen ratio, Crs respiratory system compliance, PaCO 2 arterial pressure of carbon dioxide, SaO 2 arterial blood saturation. Data is presented as median, first and third quartiles
  3. aSignificant differences compared to Baseline
  4. bSignificant differences compared to ARDSnet-24 h
  5. cSignificant differences compared to ARDSnet-48 h