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Table 1 Details of included trials

From: Effects of omega-3 fatty acid nutrition on mortality in septic patients: a meta-analysis of randomized controlled trials

Author

Population

Route of Administration

Details of administration

Mortality

Study

Control

Shirai, 2015

1 center, 46 patients, sepsis-induced ARDS

EN

Oxepa

Ensure Liquid

60 days

Hall, 2015

1 center, 60 patients, sepsis

PN

Omegaven

standard medical care

28 days

Burkhart, 2014

1 center, 50 patients, sepsis

PN

Omegaven

standard treatment

Hospital

Gultekin, 2014

1 center, 58 patients, severe sepsis or septic shock

PN

Omegaven + ClinOleic

ClinOleic

Unspecified

Pontes-Arruda, 2011

5 centers, 115 patients, early stages of sepsis

EN

Oxepa

Ensure Plus HN

28 days

Grau-Carmona, 2011

11 centers, 198 patients, septic patients with ALI or ARDS

EN

Oxepa

Ensure Plus HN

Unspecified

Khor, 2011

1 center, 28 patients, severe sepsis

PN

Omegaven

normal saline

normal saline

Barbosa, 2010

1 center, 25 patients, sepsis or SIRS

PN

Lipolus

NuTRIflex Lipid Special

28 days

Friesecke, 2008

1 center, 166 patients, critically ill patients (115 SIRS, 51 non-SIRS)

PN

Omegaven + Lipofundin

Lipofundin

28 days

Pontes-Arruda, 2006

1 center, 165 patients, severe sepsis or septic shock

EN

EPA-GLA enriched diet

Control Diet

28 days

Grecu, 2003

1 center, 54 (15 in ICU) patients, abdominal sepsis

PN

Omegaven + LCT

LCT

ICU

  1. ARDS acute respiratory distress syndrome, ALI acute lung injury, SIRS Systemic inflammatory response syndrome, EN enteral nutrition, PN parenteral nutrition, LCT Long-chain triglycerides, EPA eicosapentaenoic acid, GLA gamma-linolenic acid, Ensure Liquid, Ensure Plus HN, omega-3 fatty acids deficiency nutrition for EN; Lipofundin, NuTRIflex Lipid Special, ClinOleic, omega-3 fatty acids deficiency nutrition for PN; Oxepa, omega-3 fatty acids enriched nutrition for EN; Omegaven, omega-3 fatty acids enriched nutrition for PN