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Fig. 5 | BMC Anesthesiology

Fig. 5

From: Inhibition of CaMKIV relieves streptozotocin-induced diabetic neuropathic pain through regulation of HMGB1

Fig. 5

Effects of intrathecal injection of KN93 on blood glucose levels, body weights, mechanical allodynia and thermal hyperalgesia of STZ-induced diabetic rats. a. Changes in blood glucose levels after KN93 treatment. b. Effect of body weight after KN93 treatment. c. Effect of KN93 (100 μg) on STZ-induced mechanical allodynia. d. Effect of KN93 (100 μg) on STZ-induced thermal hyperalgesia. Data are presented as means ± SD. # P < 0.05 in comparison to the 0 day time point, n = 6 per group.*P < 0.05 in comparison with the DMSO group at the same time points, n = 6 per group. (i.t.cat: intrathecal catheterization; i.t.inj: intrathecal injection; STZ: streptozotocin intraperitoneal injection)

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BMC Anesthesiology

ISSN: 1471-2253

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