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Table 2 Propofol EC50, anesthesia related adverse events and recovery time (n = 30 in each)

From: The median effective concentration (EC50) of propofol with different doses of fentanyl during colonoscopy in elderly patients

 

Control

Group F0.5

group F1.0

Propofol EC50 (μg.ml−1)

3.08

2.75

2.05*

95 % CI (μg.ml−1)

2.78–3.42

2.50–3.02

1.98–2.13

Adverse events

 Hypotension

2

1

1

 Bradycardia

2

3

1

 Respiratory depression

1

1

2

 PONV

2

3

6 *

 Total

7 (23.3 %)

8 (26.7 %)

10 (33.3 %)

 Awake time (min)

6.2 ± 2.4

7.8 ± 3.1

9.6 ± 3.8*

 Hospital discharge (min)

35.7 ± 5.9

38.2 ± 7.5

47.6 ± 10.2*

  1. Values are expressed as mean ± SD or number of patients
  2. * P < 0.05