Fig. 2
From: Effect of propofol and sevoflurane on the inflammatory response of patients undergoing craniotomy
The ratios of IL-6i, IL-10i, (IL-6/IL-10)i and IL-8i to baseline values IL-61, IL-101, (IL-6/IL-10)1 and IL-81 at various blood-sample draw time. Measurements (i): (1) before surgery and anaesthesia (2) during surgery, (3) at the end of surgery, (4) on the first postoperative day, (5) on the second postoperative day. The data are presented as the median values in all studied patients. a IL-6i/IL-61 concentration ratio was not significantly different at any blood-sample draw time (measurement 2, p = 0.23; measurement 3, p = 0.12; measurement 4, p = 0.40; measurement 5, p = 0.55). b IL-10i/IL-101 concentration ratio significantly increased in the propofol group at measurements 2 and 3 (measurement 2, p = 0.0001; measurement 3, p < 0.0001; measurement 4, p = 0.14; measurement 5, p = 0.38). c The (IL-6/IL-10)i/ (IL-6/IL-10)1 ratio in the propofol group significantly decreased at measurements 2 and 3 (measurement 2, p = 0.0001; measurement 3, p < 0.0001; measurement 4, p = 0.08; measurement 5, p = 0.29). d IL-8i/IL-81 concentration ratio was not significantly different at any blood-sample draw time (measurement 2, p = 0.57; measurement 3, p = 0.67; measurement 4, p = 0.15; measurement 5, p = 0.43)