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Table 2 Histological analysis

From: Experimental blunt chest trauma – cardiorespiratory effects of different mechanical ventilation strategies with high positive end-expiratory pressure: a randomized controlled study

  

HFPPV group

HP-CMV group

Group effect

  

Right

Left

Right

Left

Right

Left

Atelectasis

Non-dependent

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–3)

ns

ns

Central

0 (0–1)

0 (0–3)

0 (0–1)

0 (0–3)

ns

ns

Dependent

0 (0–3)

0 (0–3)

2 (0–3)

2.5 (1–3)

ns

P = 0.01

Edema

Non-dependent

0 (0–2)

0 (0–3)

0 (0–1)

0 (0–1)

ns

ns

Central

0 (0–3)

0 (0–3)

0 (0–1)

0 (0–2)

ns

ns

Dependent

0 (0–1)

0 (0–1)

0 (0–1)

0 (0–1)

ns

ns

Inflammation

Non-dependent

0 (0–0)

0 (0–0)

0 (0–2)

0 (0–0)

ns

ns

Central

0 (0–0)

0 (0–2)

0 (0–1)

0 (0–3)

ns

ns

Dependent

0 (0–1)

0 (0–0)

0 (0–3)

1 (0–3)

ns

P = 0.03

Hemorrhage

Non-dependent

0 (0–2)

0 (0–1)

0 (0–0)

0 (0–1)

ns

ns

Central

0 (0–1)

0 (0–2)

0 (0–3)

1 (0–2)

ns

ns

Dependent

1 (0–2)

1 (0–2)

1 (0–2)

1 (0–2)

ns

ns

  1. Histological evaluation of parenchymal damage in different lung zones of pigs in the high frequency inverse ration pressure controlled ventilation (HFPPV) and low tidal volume high PEEP ventilation (HP-CMV) groups: non-dependent (ventral), central and dependent (dorsal). Values are shown as median (minimum - maximum). The maximum score achievable was three for all parameters. Inflammation refers to accumulation of inflammatory cells in airspaces and interstitium. ns: not significant, P > 0.05