Fig. 3
From: Pretreatment of parecoxib attenuates hepatic ischemia/reperfusion injury in rats
The effect of parecoxib on the proinflammatory cytokine expression and neutrophil infiltration into the liver after hepatic I/R. Liver tissues were harvested 6 h after reperfusion from the sham, I/R, and I/R + Pare groups. TNF-α a and IL-6 b mRNA expression in the liver were measured by quantitative RT-PCR analysis. Serum TNFα c and IL-6 d levels were determined using an ELISA kit. Liver tissue myeloperoxidase (MPO) activity e, a marker for neutrophil infiltration, was determined spectrophotometrically. Data presented as means ± SE (n = 6/ group) and compared by one-way ANOVA and SNK method. *P < 0.05 vs. I/R group