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Table 3 Effects of thoracic epidural analgesia on oxygenation and pulmonary shunt fraction variables during OLV

From: The effects of thoracic epidural analgesia on oxygenation and pulmonary shunt fraction during one-lung ventilation: an meta-analysis

   Median of Means (Range)   
All available data No. of comparisons TEA group GA group WMD (95 % CI) P value
During two-lung ventilation
PaO2 (mmHg) 13 382.42(205.00 to 85.00) 377.92(191.0 to 453.00) 6.29 [0.04 to 12.17] 0.35
PaCO2 (mmHg) 10 39.67 (32.50 to 37.6) 40.23 (35.60 to 37.40) −0.21 [−1.11 to 0.68] 0.64
PvO2 (mmHg) 7 51.50(48.00 to 55.0) 51.62(48.0 to 53.30) 0.27 [−1.51 to 2.06] 0.76
Qs/Qt (%) 13 14.80 (4.90 to 22.50) 15.50 (3.95 to 21.60) 0.02[−0.47 to 0.50] 0.95
SvO2 (%) 4 85.37(83.30 to 87.10) 86.68(84.90 to 88.20) −1.22[−2.36 to −0.07] 0.58
SaO2 (%) 4 99.75(99.70 to 99.90) 99.45(99.00 to 99.90) −0.06[−0.08 to −0.04] 0.30
PH 4 7.43 (7.42 to 7.43) 7.44 (7.43 to 7.44) −0.01 [−0.02 to 0.00] 0.21
Paw (cmH2O) 4 18.63 (17.00 to 20.00) 19.03 (17.00 to 21.40) −0.24 [−1.14 to 0.66] 0.60
During one-lung ventilation within 30 min
PaO2 (mmHg) 10 166.90(118.00 to 211.00) 171.2(122.00 to 201.00) −16.52[−21.98 to -11.05] <0.01
PaCO2 (mmHg) 10 37.12 (36.10 to 44.20) 36.85(34.20 to 42.20) 0.29 [−0.53 to 1.10] 0.49
PvO2 (mmHg) 7 47.78(44.90 to 54.00) 46.14(44.50 to 51.00) 1.13 [−0.50 to 2.76] 0.17
Qs/Qt (%) 10 33.32 (27.30 to 39.50) 32.77 (26.70 to 40.60) 2.53 [1.35 to 3.72] <0.01
SvO2 (%) 4 80.53(78.30 to 82.60) 81.58(78.40 to 84.20) −1.13[−2.74 to 0.48] 0.17
SaO2 (%) 4 97.98(96.80 to 99.30) 97.65(97.30 to 98.00) 0.74[0.33 to 1.15] <0.01
PH 4 7.43 (7.42 to 7.44) 7.44 (7.42 to 7.46) −0.01 [−0.02 to 0.001] 0.41
Paw (cmH2O) 4 28.00 (23.00 to 32.50) 27.00 (24.00 to 30.90) 1.95 [1.61 to 2.28] <0.01
One-lung ventilation more than 30 min
PaO2 (mmHg) 11 162.27(117.00 to 203.00) 168.72(148.00 to 221.00) −14.23[−20.81 to -7.65] <0.01
PaCO2 (mmHg) 11 36.61 (33.90 to 44.60) 36.78 (35.00 to 44.20) −0.22 [−0.96 to 0.53] 0.57
PvO2 (mmHg) 6 44.70(42.60 to 46.10) 44.98(43.40 to 46.60) −0.61[−2.23 to 1.02] 0.46
Qs/Qt (%) 12 34.40 (33.60 to 42.70) 32.67 (32.10 to 40.90) 2.77 [1.81 to 3.74] <0.01
SvO2 (%) 6 79.33(77.40 to 81.10) 81.97(78.50 to 83.90) −2.39[−3.73 to −0.99] <0.01
SaO2 (%) 6 97.68(96.60 to 98.10) 98.20(97.20 to 99.00) −0.63[−1.23 to −0.04] 0.04
PH 6 7.43 (7.43 to 7.44) 7.44 (7.41 to 7.46) 0.00 [−0.01 to 0.01] 0.50
Paw (cmH2O) 6 26.80 (24.00 to 32.50) 26.72 (24.00 to 31.40) 0.87 [0.54 to 1.20] <0.01
Re-two ventilation
PaO2 (mmHg) 7 322.28(173.00 to 482.00) 307.28(168.00 to 407.00) 11.54[−4.25 to 27.34] 0.15
PaCO2 (mmHg) 3 37.8 (34.00 to 46.10) 35.6 (34.90 to 36.90) −0.60 [−3.03 to 1.83] 0.63
PvO2 (mmHg) 5 47.82(43.00 to 50.00) 48.68(46.20 to 51.00) 0.06[−2.24 to 2.36] 0.96
Qs/Qt (%) 6 18.55(15.30 to 24.50) 20.15(15.50 to 24.80) −1.27 [−2.73 to 0.20] 0.09
SvO2 (%) 2 81.90(81.50 to 82.30) 85.30(85.30 to 85.30) −3.62[−6.28 to −0.95] 0.80
SaO2 (%) 2 99.75(99.70 to 99.80) 99.00 (99.00 to 99.00) 0.75[0.52 to 0.98] 0.67
PH 2 7.42 (7.41 to 7.42) 7.42 (7.42 to 7.42) 0.00 [−0.03 to 0.02] 0.77
Paw (cmH2O) 2 19.00 (18.00 to 20.00) 18.00 (18.00 to 18.00) 0.95 [−0.81 to 2.71] 0.29
  1. Data were presented as Mean and rang in bracket