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Table 2 Effects of thoracic epidural analgesia on hemodynamics variables during OLV

From: The effects of thoracic epidural analgesia on oxygenation and pulmonary shunt fraction during one-lung ventilation: an meta-analysis

   Median of Means (Range)   
All available data No. of comparisons TEA group GA group WMD (95 % CI) P value
During two-lung ventilation
HR(beat / min) 7 72.98 (68.80 to 83.00) 73.71 (69.00 to 78.00) −1.33 [−5.16 to 2.50] 0.50
MAP(mmHg) 5 83.62 (76.00 to 87.00) 86.26. (75.00 to 93.00) −2.28 [−5.51 to 0.95] 0.17
CO (L/min) 2 5.50 (5.20 to 5.80) 4.90 (4.90 to 4.90) 0.55 [−0.21 to 1.30] 0.16
CVP (cmH2O) 3 7.00 (6.00 to 8.00) 8.00 (6.00 to 9.00) −1.00 [−3.94 to 1.95] 0.51
SVR (dynes · sec · cm−5) 3 1180.70(1022.00 to 1308.00) 1401.67(1395.00 to 1405.00) −246.16[−408.55 to -83.77] 0.29
MPAP (mmHg) 3 20.67 (18.00 to 22.00) 18.67 (18.00 to 19.00) 2.09 [−0.94 to 5.13] 0.18
PAOP(mmHg) 2 12.50 (12.00 to 13.00) 13.00 (13.00 to 13.00) −0.59 [−2.48 to 1.31] 0.55
During one-lung ventilation within 30 min
HR(beat / min) 7 74.14 (66.00 to 85.00) 75.48 (73.20 to 80.00) −3.28 [−5.89 to −0.67] 0.01
MAP(mmHg) 7 85.11 (81.00 to 89.00) 93.29 (87.60 to 100.00) −6.64 [−9.57 to −3.71] <0.01
CO (L/min) 2 5.40 (5.40 to 5.40) 5.70 (5.70 to 5.70) −0.30 [−1.15 to 0.55] 0.49
CVP (cmH2O) 3 8.30 (7.00 to 10.00) 9.00 (8.00 to 11.00) −0.61 [−1.72, 0.49] 0.28
SVR (dynes · sec · cm−5) 3 1003.33(890.00 to 1124.00) 1349.67(1141.00 to 1454.00) −319.99[−447.05 to -192.94] <0.01
MPAP (mmHg) 3 20.00 (19.00 to 22.00) 23.00 (23.00 to 23.00) −3.18 [−5.07 to −1.28] <0.01
PAOP(mmHg) 2 12.00 (12.00 to 12.00) 13.00 (13.00 to 13.00) −1.00 [−2.87 to 0.87] 0.30
One-lung ventilation more than 30 min
HR(beat / min) 6 76.00 (75.00 to 87.00) 75.32 (71.50 to 80.00) −0.94 [−3.81 to 1.92] 0.52
MAP(mmHg) 6 84.12 (75.00 to 87.00) 91.85 (85.80 to 98.00) −6.33 [−9.25 to −3.41] <0.01
CO (L/min) 4 5.55 (4.70 to 6.10) 5.55 (5.50 to 5.60) −0.07 [−0.64 to 0.51] 0.82
CVP (cmH2O) 4 7.75 (7.00 to 9.00) 8.00 (7.00 to 9.00) −0.37 [−1.24 to 0.51] 0.41
SVR (dynes · sec · cm−5) 4 1168.50(981.00 to 1356.00) 1209.00(1209.00 to 1209.00) −38.17[−201.75 to 125.42] 0.07
MPAP (mmHg) 4 20.00 (18.00 to 21.00) 22.50 (22.00 to 23.00) −2.05 [−3.35 to −0.75] <0.01
PAOP(mmHg) 4 12.50 (12.00 to 13.00) 13.50 (13.00 to 14.00) −1.11 [−2.40 to 0.18] 0.09
Re-two ventilation
HR(beat / min) 5 74.40 (65.00 to 87.00) 71.60 (67.00 to 78.00) −0.41 [−4.08 to 3.25] 0.82
MAP(mmHg) 5 84.40 (81.00 to 87.00) 95.80 (92.00 to 95.00) −11.83 [−15.87 to −7.79] <0.01
CO (L/min) 2 5.55 (5.50 to 5.60) 5.20 (5.20 to 5.20) 0.35 [−0.58 to 1.29] 0.46
CVP (cmH2O) 3 7.67 (7.00 to 9.00) 6.33 (6.00 to 7.00) 1.20 [−0.15 to 2.55] 0.08
SVR (dynes · sec · cm−5) 3 1157.00(1052.00 to 1316.00) 1358.67(1226.00 to 1425.00) −186.69[−312.37 to −61.01] <0.01
MPAP (mmHg) 3 19.67 (18.00 to 21.00) 21.33 (21.00 to 22.00) −1.77 [−3.61 to 0.07] 0.06
PAOP(mmHg) 2 11.00 (10.00 to 12.00) 12.00 (12.00 to 12.00) −1.03[−2.75 to 0.68] 0.24
  1. Data were presented as Mean and rang in bracket