Table 2 Effects of thoracic epidural analgesia on hemodynamics variables during OLV
Median of Means (Range) | |||||
|---|---|---|---|---|---|
All available data | No. of comparisons | TEA group | GA group | WMD (95 % CI) | P value |
During two-lung ventilation | |||||
HR(beat / min) | 7 | 72.98 (68.80 to 83.00) | 73.71 (69.00 to 78.00) | −1.33 [−5.16 to 2.50] | 0.50 |
MAP(mmHg) | 5 | 83.62 (76.00 to 87.00) | 86.26. (75.00 to 93.00) | −2.28 [−5.51 to 0.95] | 0.17 |
CO (L/min) | 2 | 5.50 (5.20 to 5.80) | 4.90 (4.90 to 4.90) | 0.55 [−0.21 to 1.30] | 0.16 |
CVP (cmH2O) | 3 | 7.00 (6.00 to 8.00) | 8.00 (6.00 to 9.00) | −1.00 [−3.94 to 1.95] | 0.51 |
SVR (dynes · sec · cm−5) | 3 | 1180.70(1022.00 to 1308.00) | 1401.67(1395.00 to 1405.00) | −246.16[−408.55 to -83.77] | 0.29 |
MPAP (mmHg) | 3 | 20.67 (18.00 to 22.00) | 18.67 (18.00 to 19.00) | 2.09 [−0.94 to 5.13] | 0.18 |
PAOP(mmHg) | 2 | 12.50 (12.00 to 13.00) | 13.00 (13.00 to 13.00) | −0.59 [−2.48 to 1.31] | 0.55 |
During one-lung ventilation within 30 min | |||||
HR(beat / min) | 7 | 74.14 (66.00 to 85.00) | 75.48 (73.20 to 80.00) | −3.28 [−5.89 to −0.67] | 0.01 |
MAP(mmHg) | 7 | 85.11 (81.00 to 89.00) | 93.29 (87.60 to 100.00) | −6.64 [−9.57 to −3.71] | <0.01 |
CO (L/min) | 2 | 5.40 (5.40 to 5.40) | 5.70 (5.70 to 5.70) | −0.30 [−1.15 to 0.55] | 0.49 |
CVP (cmH2O) | 3 | 8.30 (7.00 to 10.00) | 9.00 (8.00 to 11.00) | −0.61 [−1.72, 0.49] | 0.28 |
SVR (dynes · sec · cm−5) | 3 | 1003.33(890.00 to 1124.00) | 1349.67(1141.00 to 1454.00) | −319.99[−447.05 to -192.94] | <0.01 |
MPAP (mmHg) | 3 | 20.00 (19.00 to 22.00) | 23.00 (23.00 to 23.00) | −3.18 [−5.07 to −1.28] | <0.01 |
PAOP(mmHg) | 2 | 12.00 (12.00 to 12.00) | 13.00 (13.00 to 13.00) | −1.00 [−2.87 to 0.87] | 0.30 |
One-lung ventilation more than 30 min | |||||
HR(beat / min) | 6 | 76.00 (75.00 to 87.00) | 75.32 (71.50 to 80.00) | −0.94 [−3.81 to 1.92] | 0.52 |
MAP(mmHg) | 6 | 84.12 (75.00 to 87.00) | 91.85 (85.80 to 98.00) | −6.33 [−9.25 to −3.41] | <0.01 |
CO (L/min) | 4 | 5.55 (4.70 to 6.10) | 5.55 (5.50 to 5.60) | −0.07 [−0.64 to 0.51] | 0.82 |
CVP (cmH2O) | 4 | 7.75 (7.00 to 9.00) | 8.00 (7.00 to 9.00) | −0.37 [−1.24 to 0.51] | 0.41 |
SVR (dynes · sec · cm−5) | 4 | 1168.50(981.00 to 1356.00) | 1209.00(1209.00 to 1209.00) | −38.17[−201.75 to 125.42] | 0.07 |
MPAP (mmHg) | 4 | 20.00 (18.00 to 21.00) | 22.50 (22.00 to 23.00) | −2.05 [−3.35 to −0.75] | <0.01 |
PAOP(mmHg) | 4 | 12.50 (12.00 to 13.00) | 13.50 (13.00 to 14.00) | −1.11 [−2.40 to 0.18] | 0.09 |
Re-two ventilation | |||||
HR(beat / min) | 5 | 74.40 (65.00 to 87.00) | 71.60 (67.00 to 78.00) | −0.41 [−4.08 to 3.25] | 0.82 |
MAP(mmHg) | 5 | 84.40 (81.00 to 87.00) | 95.80 (92.00 to 95.00) | −11.83 [−15.87 to −7.79] | <0.01 |
CO (L/min) | 2 | 5.55 (5.50 to 5.60) | 5.20 (5.20 to 5.20) | 0.35 [−0.58 to 1.29] | 0.46 |
CVP (cmH2O) | 3 | 7.67 (7.00 to 9.00) | 6.33 (6.00 to 7.00) | 1.20 [−0.15 to 2.55] | 0.08 |
SVR (dynes · sec · cm−5) | 3 | 1157.00(1052.00 to 1316.00) | 1358.67(1226.00 to 1425.00) | −186.69[−312.37 to −61.01] | <0.01 |
MPAP (mmHg) | 3 | 19.67 (18.00 to 21.00) | 21.33 (21.00 to 22.00) | −1.77 [−3.61 to 0.07] | 0.06 |
PAOP(mmHg) | 2 | 11.00 (10.00 to 12.00) | 12.00 (12.00 to 12.00) | −1.03[−2.75 to 0.68] | 0.24 |