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Table 3 Comparisons of LOS and costs with sensitivity analysis and subgroup analysis

From: The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation – a cost analysis

All study patients

 Variable

ECCO2R

Control

p value

 Days [range] or Euro [SD]

(n = 21)

(n = 21)

 Median length of stay in ICU

15 [4–137]

30 [4–66]

0.58

 Median length of stay in hospital

23 [4–137]

42 [4–248]

0.05

 Median duration of invasive MV

0 [0–47]

21 [4–47]

<0.001

 Mean costs for ECCO2R

7717 [7835]

-

-

 Mean total ICU costs

38460 [43878]

33291 [22572]

0.63

 Mean total hospital costs

41134 [43005]

39366 [29903]

0.88

 Mean hospital costs with maximal values

53689 [56406]

54155 [41133]

0.98

 Mean hospital costs with minimal values

28616 [18721]

24629 [18721]

0.61

Subgroup analysis after exclusion of patients with lung transplantation

 Variable

ECCO2R

Control

p value

 Days [range] or Euro [SD]

(n = 17)

(n = 17)

 Median length of stay in ICU

13 [4–137]

30 [4–66]

0.41

 Median length of stay in hospital

22 [4–137]

42 [4–248]

0.23

 Median duration of invasive MV

0 [0–47]

21 [1–47]

0.001

 Mean costs for ECCO2R

5972 [6522]

-

-

 Mean total ICU costs

24989 [35273]

33581 [23656]

0.41

 Mean total hospital costs

33843 [40866]

39731 [31507]

0.64

 Mean hospital costs with maximal values

44314 [53924]

54656 [43340]

0.54

 Mean hospital costs with minimal values

23405 [27856]

24857 [19727]

0.86

Subgroup analysis of patients with COPD

 Variable

ECCO2R

Control

p value

 Days [range] or Euro [SD]

(n = 12)

(n = 12)

 Median length of stay in ICU

11 [4–23]

35 [4–66]

0.004

 Median length of stay in hospital

17 [4–43]

51 [4–248]

0.04

 Median duration of invasive MV

0 [0–22]

27 [4–47]

0.001

 Mean costs for ECCO2R

4472 [1269]

-

-

 Mean total ICU costs

13194 [4611]

39304 [25163]

0.004

 Mean total hospital costs

19610 [7509]

46552 [34558]

0.02

 Mean hospital costs with maximal values

25298 [10115]

64040 [47536]

0.01

 Mean hospital costs with minimal values

13942 [4938]

29124 [21641]

0.03

  1. Abbreviations: LOS length of stay, SD standard deviation, COPD chronic obstructive pulmonary disease, ICU intensive care unit, MV mechanical ventilation, ECCO 2 R Extracorporeal carbon dioxide removal
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BMC Anesthesiology

ISSN: 1471-2253

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